Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
3R01DE005937-15A1S1
Application #
2597676
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1981-03-01
Project End
1998-02-28
Budget Start
1997-05-01
Budget End
1998-02-28
Support Year
15
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Orthopedics
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Kinney, R C; Schwartz, Z; Week, K et al. (2005) Human articular chondrocytes exhibit sexual dimorphism in their responses to 17beta-estradiol. Osteoarthritis Cartilage 13:330-7
Schwartz, Z; Carney, D H; Crowther, R S et al. (2005) Thrombin peptide (TP508) treatment of rat growth plate cartilage cells promotes proliferation and retention of the chondrocytic phenotype while blocking terminal endochondral differentiation. J Cell Physiol 202:336-43
Schwartz, Z; Graham, E J; Wang, L et al. (2005) Phospholipase A2 activating protein (PLAA) is required for 1alpha,25(OH)2D3 signaling in growth plate chondrocytes. J Cell Physiol 203:54-70
Gay, I; Schwartz, Z; Sylvia, V L et al. (2004) Lysophospholipid regulates release and activation of latent TGF-beta1 from chondrocyte extracellular matrix. Biochim Biophys Acta 1684:18-28
Boyan, B D; Schwartz, Zvi (2004) Rapid vitamin D-dependent PKC signaling shares features with estrogen-dependent PKC signaling in cartilage and bone. Steroids 69:591-7
Boyan, B D; Jennings, E G; Wang, L et al. (2004) Mechanisms regulating differential activation of membrane-mediated signaling by 1alpha,25(OH)2D3 and 24R,25(OH)2D3. J Steroid Biochem Mol Biol 89-90:309-15
Lohmann, C H; Schwartz, Z; Liu, Y et al. (2003) Pulsed electromagnetic fields affect phenotype and connexin 43 protein expression in MLO-Y4 osteocyte-like cells and ROS 17/2.8 osteoblast-like cells. J Orthop Res 21:326-34
Boyan, B D; Sylvia, V L; Frambach, T et al. (2003) Estrogen-dependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membrane-mediated and inhibited by tamoxifen. Endocrinology 144:1812-24
Boyan, Barbara D; Dean, David D; Sylvia, Victor L et al. (2003) Steroid hormone action in musculoskeletal cells involves membrane receptor and nuclear receptor mechanisms. Connect Tissue Res 44 Suppl 1:130-5
Schwartz, Z; Shaked, D; Hardin, R R et al. (2003) 1alpha,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-beta activity via phospholipase A2-dependent production of lysophospholipid. Steroids 68:423-37

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