Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE007559-13
Application #
2129862
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1987-09-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Dentistry
Type
Schools of Dentistry
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Alblowi, Jazia; Kayal, Rayyan A; Siqueira, Michelle et al. (2009) High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing. Am J Pathol 175:1574-85
Behl, Yugal; Krothapalli, Padmaja; Desta, Tesfahun et al. (2009) FOXO1 plays an important role in enhanced microvascular cell apoptosis and microvascular cell loss in type 1 and type 2 diabetic rats. Diabetes 58:917-25
Graves, Dana T; Fine, Daniel; Teng, Yen-Tung A et al. (2008) The use of rodent models to investigate host-bacteria interactions related to periodontal diseases. J Clin Periodontol 35:89-105
Behl, Yugal; Krothapalli, Padmaja; Desta, Tesfahun et al. (2008) Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy. Am J Pathol 172:1411-8
Alikhani, Mani; Maclellan, Christine M; Raptis, Markos et al. (2007) Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor. Am J Physiol Cell Physiol 292:C850-6
Liu, R; Bal, H S; Desta, T et al. (2006) Diabetes enhances periodontal bone loss through enhanced resorption and diminished bone formation. J Dent Res 85:510-4
Leone, Cataldo W; Bokhadhoor, Haneen; Kuo, David et al. (2006) Immunization enhances inflammation and tissue destruction in response to Porphyromonas gingivalis. Infect Immun 74:2286-92
Alikhani, Mani; Alikhani, Zoubin; Graves, Dana T (2005) FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. J Biol Chem 280:12096-102