Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE009691-06
Application #
2130706
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1991-01-01
Project End
1997-08-31
Budget Start
1996-08-01
Budget End
1997-08-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Hajishengallis, George; Sharma, Ashu; Russell, Michael W et al. (2002) Interactions of oral pathogens with toll-like receptors: possible role in atherosclerosis. Ann Periodontol 7:72-8
Russell, Michael W; Mestecky, Jiri (2002) Humoral immune responses to microbial infections in the genital tract. Microbes Infect 4:667-77
Hajishengallis, George; Martin, Michael; Sojar, Hakimuddin T et al. (2002) Dependence of bacterial protein adhesins on toll-like receptors for proinflammatory cytokine induction. Clin Diagn Lab Immunol 9:403-11
Smith, P D; Smythies, L E; Mosteller-Barnum, M et al. (2001) Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities. J Immunol 167:2651-6
Russell, M W; Sibley, D A; Nikolova, E B et al. (1997) IgA antibody as a non-inflammatory regulator of immunity. Biochem Soc Trans 25:466-70
Mestecky, J; Russell, M W (1997) Mucosal immunoglobulins and their contribution to defence mechanisms: an overview. Biochem Soc Trans 25:457-62
Nikolova, E B; Russell, M W (1995) Dual function of human IgA antibodies: inhibition of phagocytosis in circulating neutrophils and enhancement of responses in IL-8-stimulated cells. J Leukoc Biol 57:875-82
Nikolova, E B; Tomana, M; Russell, M W (1994) The role of the carbohydrate chains in complement (C3) fixation by solid-phase-bound human IgA. Immunology 82:321-7
Nikolova, E B; Tomana, M; Russell, M W (1994) All forms of human IgA antibodies bound to antigen interfere with complement (C3) fixation induced by IgG or by antigen alone. Scand J Immunol 39:275-80
Hajishengallis, G; Nikolova, E; Russell, M W (1992) Inhibition of Streptococcus mutans adherence to saliva-coated hydroxyapatite by human secretory immunoglobulin A (S-IgA) antibodies to cell surface protein antigen I/II: reversal by IgA1 protease cleavage. Infect Immun 60:5057-64