Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE009820-05
Application #
2130749
Study Section
Physiological Sciences Study Section (PSF)
Project Start
1992-03-15
Project End
1998-03-14
Budget Start
1996-03-15
Budget End
1998-03-14
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Dentistry
Type
Schools of Dentistry
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Lis, Maciej; Bhatt, Sanjay; Schoenly, Nathan E et al. (2013) Chemical genomic screening of a Saccharomyces cerevisiae genomewide mutant collection reveals genes required for defense against four antimicrobial peptides derived from proteins found in human saliva. Antimicrob Agents Chemother 57:840-7
Lis, Maciej; Liu, Teresa T; Barker, Katherine S et al. (2010) Antimicrobial peptide MUC7 12-mer activates the calcium/calcineurin pathway in Candida albicans. FEMS Yeast Res 10:579-86
Lis, Maciej; Fuss, Jason R; Bobek, Libuse A (2009) Exploring the mode of action of antimicrobial peptide MUC7 12-mer by fitness profiling of Saccharomyces cerevisiae genomewide mutant collection. Antimicrob Agents Chemother 53:3762-9
Lis, Maciej; Bobek, Libuse A (2008) Proteomic and metabolic characterization of a Candida albicans mutant resistant to the antimicrobial peptide MUC7 12-mer. FEMS Immunol Med Microbiol 54:80-91
Intini, Giuseppe; Andreana, Sebastiano; Buhite, Robert J et al. (2008) A comparative analysis of bone formation induced by human demineralized freeze-dried bone and enamel matrix derivative in rat calvaria critical-size bone defects. J Periodontol 79:1217-24
Wei, Guo-Xian; Campagna, Alexander N; Bobek, Libuse A (2007) Factors affecting antimicrobial activity of MUC7 12-mer, a human salivary mucin-derived peptide. Ann Clin Microbiol Antimicrob 6:14
Wei, Guo-Xian; Campagna, Alexander N; Bobek, Libuse A (2006) Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm. J Antimicrob Chemother 57:1100-9
Li, Shimin; Intini, Giuseppe; Bobek, Libuse A (2006) Modulation of MUC7 mucin expression by exogenous factors in airway cells in vitro and in vivo. Am J Respir Cell Mol Biol 35:95-102
Li, Shimin; Bobek, Libuse A (2006) Functional analysis of human MUC7 mucin gene 5'-flanking region in lung epithelial cells. Am J Respir Cell Mol Biol 35:593-601
Wei, Guo-Xian; Bobek, Libuse A (2005) Human salivary mucin MUC7 12-mer-L and 12-mer-D peptides: antifungal activity in saliva, enhancement of activity with protease inhibitor cocktail or EDTA, and cytotoxicity to human cells. Antimicrob Agents Chemother 49:2336-42

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