Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
2R01DE012110-13A2
Application #
6286195
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Program Officer
Zhang, Guo He
Project Start
1984-12-01
Project End
2005-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
13
Fiscal Year
2001
Total Cost
$331,088
Indirect Cost
Name
Yale University
Department
Orthopedics
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Carlson, Jodi; Cui, Weiguo; Zhang, Qing et al. (2009) Role of MKP-1 in osteoclasts and bone homeostasis. Am J Pathol 175:1564-73
Carlson, Jodi; Zhang, Qing; Bennett, Anton et al. (2009) Deletion of mitogen-activated protein kinase phosphatase 1 modifies the response to mechanical bone marrow ablation in a mouse model. Comp Med 59:221-6
Zhang, Qing; Cuartas, Esteban; Mehta, Nozer et al. (2008) Replacement of bone marrow by bone in rat femurs: the bone bioreactor. Tissue Eng Part A 14:237-46
Cui, Weiguo; Cuartas, Esteban; Ke, Juan et al. (2007) CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts. Proc Natl Acad Sci U S A 104:14436-41
Cui, Weiguo; Ke, Juan Zhang; Zhang, Qing et al. (2006) The intracellular domain of CD44 promotes the fusion of macrophages. Blood 107:796-805
Vignery, Agnes (2005) Macrophage fusion: are somatic and cancer cells possible partners? Trends Cell Biol 15:188-93
Li, Hongmei; Cuartas, Esteban; Cui, Weiguo et al. (2005) IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. J Exp Med 201:1169-77
Han, X; Sterling, H; Chen, Y et al. (2000) CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleation. J Biol Chem 275:37984-92
Saginario, C; Sterling, H; Beckers, C et al. (1998) MFR, a putative receptor mediating the fusion of macrophages. Mol Cell Biol 18:6213-23