Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK009012-33S1
Application #
6062263
Study Section
General Medicine B Study Section (GMB)
Program Officer
May, Michael K
Project Start
1976-06-01
Project End
2000-11-30
Budget Start
1998-04-01
Budget End
2000-11-30
Support Year
33
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of California Riverside
Department
Biochemistry
Type
Schools of Earth Sciences/Natur
DUNS #
City
Riverside
State
CA
Country
United States
Zip Code
92521
Sequeira, Vanessa B; Rybchyn, Mark S; Tongkao-On, Wannit et al. (2012) The role of the vitamin D receptor and ERp57 in photoprotection by 1?,25-dihydroxyvitamin D3. Mol Endocrinol 26:574-82
Mizwicki, Mathew T; Menegaz, Danusa; Zhang, Jun et al. (2012) Genomic and nongenomic signaling induced by 1?,25(OH)2-vitamin D3 promotes the recovery of amyloid-? phagocytosis by Alzheimer's disease macrophages. J Alzheimers Dis 29:51-62
Menegaz, Danusa; Mizwicki, Mathew T; Barrientos-Duran, Antonio et al. (2011) Vitamin D receptor (VDR) regulation of voltage-gated chloride channels by ligands preferring a VDR-alternative pocket (VDR-AP). Mol Endocrinol 25:1289-300
Dixon, Katie M; Norman, Anthony W; Sequeira, Vanessa B et al. (2011) 1ýý,25(OH)ýýý-vitamin D and a nongenomic vitamin D analogue inhibit ultraviolet radiation-induced skin carcinogenesis. Cancer Prev Res (Phila) 4:1485-94
Mizwicki, Mathew T; Menegaz, Danusa; Yaghmaei, Sepideh et al. (2010) A molecular description of ligand binding to the two overlapping binding pockets of the nuclear vitamin D receptor (VDR): structure-function implications. J Steroid Biochem Mol Biol 121:98-105
Norman, Anthony W; Bouillon, Roger (2010) Vitamin D nutritional policy needs a vision for the future. Exp Biol Med (Maywood) 235:1034-45
Masoumi, Ava; Goldenson, Ben; Ghirmai, Senait et al. (2009) 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. J Alzheimers Dis 17:703-17
Bula, Craig M; Bishop, June E; Norman, Anthony W (2007) Conservative mutageneic perturbations of amino acids connecting helix 12 in the 1alpha,25(OH)2-D3 receptor (VDR) to the ligand cause significant transactivational effects. J Steroid Biochem Mol Biol 103:286-92
Norman, Anthony W; Bouillon, Roger; Whiting, Susan J et al. (2007) 13th Workshop consensus for vitamin D nutritional guidelines. J Steroid Biochem Mol Biol 103:204-5
Mizwicki, Mathew T; Bula, Craig M; Bishop, June E et al. (2007) New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model. J Steroid Biochem Mol Biol 103:243-62