Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK011270-26S1
Application #
2136678
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1978-05-01
Project End
1996-11-30
Budget Start
1993-12-01
Budget End
1994-11-30
Support Year
26
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Najjar, S M; Broyart, J P; Hampp, L T et al. (2001) Sucrase-alpha-dextrinase in the spontaneously diabetic BioBreed Wistar rat: altered intracellular carbohydrate processing. J Cell Biochem 81:252-61
Najjar, S M; Broyart, J P; Hampp, L T et al. (2001) Intestinal aminooligopeptidase in diabetic BioBreed rat: altered posttranslational processing and trafficking. Am J Physiol Gastrointest Liver Physiol 280:G104-12
Nudell, D M; Santiago, N A; Zhu, J S et al. (1993) Intestinal lactase: maturational excess expression of mRNA over enzyme protein. Am J Physiol 265:G1108-15
Quan, R; Gray, G M (1993) Sucrase-alpha-dextrinase in the rat. Postinsertional conversion to inactive molecular species by a carbohydrate-free diet. J Clin Invest 91:2785-90
Gray, G M (1993) Intestinal lactase: what defines the decline? Gastroenterology 105:931-4
Gray, G M (1992) Starch digestion and absorption in nonruminants. J Nutr 122:172-7
Najjar, S M; Hampp, L T; Rabkin, R et al. (1992) Altered intestinal and renal brush border amino-oligopeptidase structure in diabetes and metabolic acidosis: normal and biobreed (BB) rats. Metabolism 41:76-84
Najjar, S M; Hampp, L T; Rabkin, R et al. (1991) Sucrase-alpha-dextrinase in diabetic BioBreed rats: reversible alteration of subunit structure. Am J Physiol 260:G275-83
Shapiro, G L; Bulow, S D; Conklin, K A et al. (1991) Postinsertional processing of sucrase-alpha-dextrinase precursor to authentic subunits: multiple step cleavage by trypsin. Am J Physiol 261:G847-57
Zhu, J S; Conklin, K A; Scheving, L A et al. (1991) Structural and functional correlates of sucrase-alpha-dextrinase in intact brush border membranes. Biochemistry 30:10399-408

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