Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK017609-30
Application #
6738945
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Serrano, Jose
Project Start
1977-05-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
30
Fiscal Year
2004
Total Cost
$468,805
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Yovchev, Mladen; Jaber, Fadi L; Lu, Zhonglei et al. (2016) Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location. Sci Rep 6:19275
Yovchev, Mladen I; Xue, Yuhua; Shafritz, David A et al. (2014) Repopulation of the fibrotic/cirrhotic rat liver by transplanted hepatic stem/progenitor cells and mature hepatocytes. Hepatology 59:284-95
Menthena, Anuradha; Koehler, Christoph I; Sandhu, Jaswinderpal S et al. (2011) Activin A, p15INK4b signaling, and cell competition promote stem/progenitor cell repopulation of livers in aging rats. Gastroenterology 140:1009-20
Shafritz, David A; Oertel, Michael (2011) Model systems and experimental conditions that lead to effective repopulation of the liver by transplanted cells. Int J Biochem Cell Biol 43:198-213
Oertel, Michael; Shafritz, David A (2008) Stem cells, cell transplantation and liver repopulation. Biochim Biophys Acta 1782:61-74
Oertel, Michael; Menthena, Anuradha; Chen, Yuan-Qing et al. (2008) Purification of fetal liver stem/progenitor cells containing all the repopulation potential for normal adult rat liver. Gastroenterology 134:823-32
Oertel, Michael; Menthena, Anuradha; Chen, Yuan-Qing et al. (2007) Comparison of hepatic properties and transplantation of Thy-1(+) and Thy-1(-) cells isolated from embryonic day 14 rat fetal liver. Hepatology 46:1236-45
Nierhoff, Dirk; Levoci, Lauretta; Schulte, Sigrid et al. (2007) New cell surface markers for murine fetal hepatic stem cells identified through high density complementary DNA microarrays. Hepatology 46:535-47
Shafritz, David A; Oertel, Michael; Menthena, Anuradha et al. (2006) Liver stem cells and prospects for liver reconstitution by transplanted cells. Hepatology 43:S89-98
Gouon-Evans, Valerie; Boussemart, Lise; Gadue, Paul et al. (2006) BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat Biotechnol 24:1402-11

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