Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK019912-20
Application #
2137398
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1978-05-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rosalind Franklin University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
069501252
City
North Chicago
State
IL
Country
United States
Zip Code
60064
Kemp, Robert G; Gunasekera, Dhammika (2002) Evolution of the allosteric ligand sites of mammalian phosphofructo-1-kinase. Biochemistry 41:9426-30
Chang, Simon H; Kemp, Robert G (2002) Role of Ser530, Arg292, and His662 in the allosteric behavior of rabbit muscle phosphofructokinase. Biochem Biophys Res Commun 290:670-5
Wang, X; Kemp, R G (2001) Reaction path of phosphofructo-1-kinase is altered by mutagenesis and alternative substrates. Biochemistry 40:3938-42
Deng, Z; Wang, X; Kemp, R G (2000) Site-directed mutagenesis of the fructose 6-phosphate binding site of the pyrophosphate-dependent phosphofructokinase of Entamoeba histolytica. Arch Biochem Biophys 380:56-62
Gunasekera, D; Kemp, R G (2000) Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene. Gene 260:103-12
Wang, X; Kemp, R G (1999) Identification of residues of Escherichia coli phosphofructokinase that contribute to nucleotide binding and specificity. Biochemistry 38:4313-8
Deng, Z; Roberts, D; Wang, X et al. (1999) Expression, characterization, and crystallization of the pyrophosphate-dependent phosphofructo-1-kinase of Borrelia burgdorferi. Arch Biochem Biophys 371:326-31
Li, Y; Rivera, D; Ru, W et al. (1999) Identification of allosteric sites in rabbit phosphofructo-1-kinase. Biochemistry 38:16407-12
Gunasekera, D; Kemp, R G (1999) Cloning, sequencing, expression, and purification of the C isozyme of mouse phosphofructokinase. Protein Expr Purif 16:448-53
Wang, X; Deng, Z; Kemp, R G (1998) An essential methionine residue involved in substrate binding by phosphofructokinases. Biochem Biophys Res Commun 250:466-8

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