Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK021506-19
Application #
2137583
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1978-04-01
Project End
1998-10-31
Budget Start
1996-04-01
Budget End
1998-10-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Hofmann, Alan F; Zakko, Salam F; Lira, Marco et al. (2005) Novel biotransformation and physiological properties of norursodeoxycholic acid in humans. Hepatology 42:1391-8
Jover, A; Meijide, F; Soto, Victor H et al. (2004) Successful prediction of the hydrogen bond network of the 3-oxo-12alpha-hydroxy-5beta-cholan-24-oic acid crystal from resolution of the crystal structure of deoxycholic acid and its three 3,12-dihydroxy epimers. Steroids 69:379-88
Meng, Ling-Jie; Wang, Pijun; Wolkoff, Allan W et al. (2002) Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2. Hepatology 35:1031-40
Cantz, T; Nies, A T; Brom, M et al. (2000) MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells. Am J Physiol Gastrointest Liver Physiol 278:G522-31
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Gruy-Kapral, C; Little, K H; Fordtran, J S et al. (1999) Conjugated bile acid replacement therapy for short-bowel syndrome. Gastroenterology 116:15-21
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Ricci, P; Hofmann, A F; Hagey, L R et al. (1998) Adjuvant cholylsarcosine during ursodeoxycholic acid treatment of primary biliary cirrhosis. Dig Dis Sci 43:1292-5
Hagey, L R; Schteingart, C D; Rossi, S S et al. (1998) An N-acyl glycyltaurine conjugate of deoxycholic acid in the biliary bile acids of the rabbit. J Lipid Res 39:2119-24
Venkataramani, A; Strong, R M; Anderson, D S et al. (1998) Abnormal duodenal bile composition in patients with acalculous chronic cholecystitis. Am J Gastroenterol 93:434-41

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