The purpose of this study is to define the metabolism of biogenic amines -- i.e. serotonin, histamine, dopamine - in the different morphological types of endocrine cells and in the mast cells in the normal and abnormal human stomach and intestines and in the stomach and intestines of the rat and mouse. Methods employed include light and electron microscopic radioautography, organ culture, amine-fluorescent techniques, and thin-layer chromatography and liquid scintillation counting to separate and identify radioactive metabolites.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK025495-08
Application #
3227431
Study Section
(GCN)
Project Start
1979-04-01
Project End
1988-03-31
Budget Start
1986-04-01
Budget End
1988-03-31
Support Year
8
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129