This is a three year prospective study of 100 newly diagnosed juvenile diabetics, aged 8 to 13. It will reliably assess and systematically document the extent of depression in the child to: medical status at the time of hospital admission, adequacy of diabetic control over time, depression and anxiety in the mother (mothering one), and familial history of affective disorders. It is hypothesized that in the child capable of abstract operational thought, a brief depressive reaction may represent a """"""""mourning"""""""" for the pre-illness self and may be a good prognosticator of subsequent psychiatric/medical status. On the other hand, familial history of affective disorders and/or concurrent clinical depression in the parent may correlate with clinical depression in the parent may correlate with clinical depression in the child. A structured Clinical Interview Schedule and rating scales are used to assess depressive and related symptoms. Initial assessment is two weeks after discharge from the Metabolic Unit of Children's Hospital. Clinical and medical indices which serve as independent variables are assessed independently of the child's depression. Follow-up interviews at 1-, 4-, 8-, 12-, 18-, and 24-months serve to gather data, and to test the hypothesis made explicit and are contrasted with data from a """"""""psychiatric"""""""" child sample. Since clinical depression may be a special problem in the medical management of the diabetic child, its proper identification will enhance appropriate referral for psychological/pharmacological treatment, and will have a positive effect on the child's illness and his/her overall quality of life.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK025568-07S1
Application #
3227489
Study Section
Behavioral Medicine Study Section (BEM)
Project Start
1979-04-01
Project End
1986-11-30
Budget Start
1986-07-01
Budget End
1986-11-30
Support Year
7
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Kovacs, M; Obrosky, D S; Goldston, D et al. (1997) Major depressive disorder in youths with IDDM. A controlled prospective study of course and outcome. Diabetes Care 20:45-51
Kovacs, M; Goldston, D; Obrosky, D S et al. (1997) Psychiatric disorders in youths with IDDM: rates and risk factors. Diabetes Care 20:36-44
Kovacs, M; Mukerji, P; Iyengar, S et al. (1996) Psychiatric disorder and metabolic control among youths with IDDM. A longitudinal study. Diabetes Care 19:318-23
Pollock, M; Kovacs, M; Charron-Prochownik, D (1995) Eating disorders and maladaptive dietary/insulin management among youths with childhood-onset insulin-dependent diabetes mellitus. J Am Acad Child Adolesc Psychiatry 34:291-6
Charron-Prochownik, D; Kovacs, M; Obrosky, D S et al. (1995) Illness characteristics and psychosocial and demographic correlates of illness severity at onset of insulin-dependent diabetes mellitus among school-age children. J Pediatr Nurs 10:354-9
Kovacs, M; Mukerji, P; Drash, A et al. (1995) Biomedical and psychiatric risk factors for retinopathy among children with IDDM. Diabetes Care 18:1592-9
Kovacs, M; Ho, V; Pollock, M H (1995) Criterion and predictive validity of the diagnosis of adjustment disorder: a prospective study of youths with new-onset insulin-dependent diabetes mellitus. Am J Psychiatry 152:523-8
Kovacs, M; Charron-Prochownik, D; Obrosky, D S (1995) A longitudinal study of biomedical and psychosocial predictors of multiple hospitalizations among young people with insulin-dependent diabetes mellitus. Diabet Med 12:142-8
Goldston, D B; Kovacs, M; Ho, V Y et al. (1994) Suicidal ideation and suicide attempts among youth with insulin-dependent diabetes mellitus. J Am Acad Child Adolesc Psychiatry 33:240-6