Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK026638-18
Application #
2137893
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1979-12-01
Project End
1998-06-30
Budget Start
1995-12-01
Budget End
1998-06-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Li, N; Seetharam, S; Seetharam, B (1998) Characterization of the human transcobalamin II promoter. A proximal GC/GT box is a dominant negative element. J Biol Chem 273:16104-11
Bose, S; Seetharam, B (1997) Purification, membrane expression, and interactions of transcobalamin II receptor. Methods Enzymol 281:281-9
Bose, S; Komorowski, R; Seetharam, S et al. (1996) In vitro and in vivo inactivation of transcobalamin II receptor by its antiserum. J Biol Chem 271:4195-200
Bose, S; Feix, J; Seetharam, S et al. (1996) Dimerization of transcobalamin II receptor. Requirement of a structurally ordered lipid bilayer. J Biol Chem 271:11718-25
Bose, S; Seetharam, S; Hammond, T G et al. (1995) Regulation of expression of transcobalamin II receptor in the rat. Biochem J 310 ( Pt 3):923-9
Bose, S; Seetharam, S; Seetharam, B (1995) Membrane expression and interactions of human transcobalamin II receptor. J Biol Chem 270:8152-7
Li, N; Seetharam, S; Seetharam, B (1995) Genomic structure of human transcobalamin II: comparison to human intrinsic factor and transcobalamin I. Biochem Biophys Res Commun 208:756-64
Ramanujam, K S; Seetharam, S; Dahms, N M et al. (1994) Effect of processing inhibitors on cobalamin (vitamin B12) transcytosis in polarized opossum kidney cells. Arch Biochem Biophys 315:8-15
Li, N; Seetharam, S; Rosenblatt, D S et al. (1994) Expression of transcobalamin II mRNA in human tissues and cultured fibroblasts from normal and transcobalamin II-deficient patients. Biochem J 301 ( Pt 2):585-90
Li, N; Sood, G K; Seetharam, S et al. (1994) Polymorphism of human transcobalamin II: substitution of proline and/or glutamine residues by arginine. Biochim Biophys Acta 1219:515-20

Showing the most recent 10 out of 26 publications