Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK030834-14
Application #
2138520
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1982-04-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Elahi, Dariush; Ruff, Dennis A; Carlson, Olga D et al. (2016) Does GLP-1 suppress its own basal secretion? Endocr Res 41:16-20
Liu, Z; Stanojevic, V; Avadhani, S et al. (2011) Stromal cell-derived factor-1 (SDF-1)/chemokine (C-X-C motif) receptor 4 (CXCR4) axis activation induces intra-islet glucagon-like peptide-1 (GLP-1) production and enhances beta cell survival. Diabetologia 54:2067-76
Tomas, Eva; Habener, Joel F (2010) Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis. Trends Endocrinol Metab 21:59-67
Liu, Z; Habener, J F (2009) Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2). Diabetologia 52:1589-98
Liu, Zhengyu; Habener, Joel F (2008) Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. J Biol Chem 283:8723-35
Elahi, Dariush; Egan, Josephine M; Shannon, Richard P et al. (2008) GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring) 16:1501-9
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Gragnoli, Claudia; Gragnoli, Claudio; Milord, Edrice et al. (2005) Linkage study of the glucagon receptor gene with type 2 diabetes mellitus in Italians. Metabolism 54:786-7
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