Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK031056-11S1
Application #
3229818
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1982-09-30
Project End
1997-08-31
Budget Start
1992-09-01
Budget End
1993-08-31
Support Year
11
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Boston University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Simons, Elizabeth R (2010) Measurement of phagocytosis and of the phagosomal environment in polymorphonuclear phagocytes by flow cytometry. Curr Protoc Cytom Chapter 9:Unit9.31
Bernardo, John; Long, Heidi J; Simons, Elizabeth R (2010) Initial cytoplasmic and phagosomal consequences of human neutrophil exposure to Staphylococcus epidermidis. Cytometry A 77:243-52
Herrmann, Jens Martin; Bernardo, John; Long, Heidi J et al. (2007) Sequential chemotactic and phagocytic activation of human polymorphonuclear neutrophils. Infect Immun 75:3989-98
Bernardo, John; Hartlaub, Hilary; Yu, Xin et al. (2002) Immune complex stimulation of human neutrophils involves a novel Ca2+/H+ exchanger that participates in the regulation of cytoplasmic pH: flow cytometric analysis of Ca2+/pH responses by subpopulations. J Leukoc Biol 72:1172-9
Mambula, S S; Simons, E R; Hastey, R et al. (2000) Human neutrophil-mediated nonoxidative antifungal activity against Cryptococcus neoformans. Infect Immun 68:6257-64
Levitz, S M; Nong, S H; Seetoo, K F et al. (1999) Cryptococcus neoformans resides in an acidic phagolysosome of human macrophages. Infect Immun 67:885-90
Christin, L; Wysong, D R; Meshulam, T et al. (1998) Human platelets damage Aspergillus fumigatus hyphae and may supplement killing by neutrophils. Infect Immun 66:1181-9
Gewirtz, A T; Seetoo, K F; Simons, E R (1998) Neutrophil degranulation and phospholipase D activation are enhanced if the Na+/H+ antiport is blocked. J Leukoc Biol 64:98-103
Bernardo, J; Billingslea, A M; Blumenthal, R L et al. (1998) Differential responses of human mononuclear phagocytes to mycobacterial lipoarabinomannans: role of CD14 and the mannose receptor. Infect Immun 66:28-35
Seetoo, K F; Schonhorn, J E; Gewirtz, A T et al. (1997) A cytosolic calcium transient is not necessary for degranulation or oxidative burst in immune complex-stimulated neutrophils. J Leukoc Biol 62:329-40

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