Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK031842-14
Application #
2138703
Study Section
Metabolism Study Section (MET)
Project Start
1983-01-01
Project End
1996-12-31
Budget Start
1996-02-27
Budget End
1996-12-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Sun, Juan; Mao, Li-Qun; Polonsky, Kenneth S et al. (2016) Pancreatic ?-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak. J Biol Chem 291:13529-34
Ren, Decheng; Sun, Juan; Mao, Liqun et al. (2014) BH3-only molecule Bim mediates ?-cell death in IRS2 deficiency. Diabetes 63:3378-87
Ren, Decheng; Sun, Juan; Wang, Changzheng et al. (2014) Role of BH3-only molecules Bim and Puma in ?-cell death in Pdx1 deficiency. Diabetes 63:2744-50
Pedersen, Morten Gram; Mosekilde, Erik; Polonsky, Kenneth S et al. (2013) Complex patterns of metabolic and Ca²? entrainment in pancreatic islets by oscillatory glucose. Biophys J 105:29-39
Klein, Samuel; Fabbrini, Elisa; Patterson, Bruce W et al. (2012) Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes. Obesity (Silver Spring) 20:1266-72
Reeds, Dominic N; Patterson, Bruce W; Okunade, Adewole et al. (2011) Ginseng and ginsenoside Re do not improve ?-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes. Diabetes Care 34:1071-6
Villareal, Dennis T; Robertson, Heather; Bell, Graeme I et al. (2010) TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes 59:479-85
Wice, Burton M; Wang, Songyan; Crimmins, Dan L et al. (2010) Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. J Biol Chem 285:19842-53
Cheverud, James M; Fawcett, Gloria L; Jarvis, Joseph P et al. (2010) Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. J Lipid Res 51:907-13
Fujimoto, Kei; Chen, Yun; Polonsky, Kenneth S et al. (2010) Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci U S A 107:10214-9

Showing the most recent 10 out of 120 publications