Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK032234-23
Application #
7431681
Study Section
Integrative and Clinical Endocrinology and Reproduction Study Section (ICER)
Program Officer
Malozowski, Saul N
Project Start
1995-07-01
Project End
2011-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
23
Fiscal Year
2008
Total Cost
$331,097
Indirect Cost

  Institution

Name
University of Texas Health Science Center Houston
Department
Biology
Type
Schools of Medicine
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225

  Publications

Schonbrunn, Agnes (2015) Editorial: Reproducibility in Research: A Cautionary Tale and Lessons Not Learned. Mol Endocrinol 29:1219-21
Schonbrunn, Agnes (2014) Editorial: Antibody can get it right: confronting problems of antibody specificity and irreproducibility. Mol Endocrinol 28:1403-7
Waser, Beatrice; Cescato, Renzo; Liu, Qisheng et al. (2012) Phosphorylation of sst2 receptors in neuroendocrine tumors after octreotide treatment of patients. Am J Pathol 180:1942-9
Körner, Meike; Waser, Beatrice; Schonbrunn, Agnes et al. (2012) Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting. Am J Surg Pathol 36:242-52
Ghosh, Madhumita; Schonbrunn, Agnes (2011) Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation. J Biol Chem 286:13561-73
Kao, Yachu J; Ghosh, Madhumita; Schonbrunn, Agnes (2011) Ligand-dependent mechanisms of sst2A receptor trafficking: role of site-specific phosphorylation and receptor activation in the actions of biased somatostatin agonists. Mol Endocrinol 25:1040-54
Cescato, Renzo; Loesch, Kimberly A; Waser, Beatrice et al. (2010) Agonist-biased signaling at the sst2A receptor: the multi-somatostatin analogs KE108 and SOM230 activate and antagonize distinct signaling pathways. Mol Endocrinol 24:240-9
Liu, Qisheng; Bee, Mark S; Schonbrunn, Agnes (2009) Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation. Mol Pharmacol 76:68-80
Liu, Q; Dewi, D A; Liu, W et al. (2008) Distinct phosphorylation sites in the SST2A somatostatin receptor control internalization, desensitization, and arrestin binding. Mol Pharmacol 73:292-304
Schonbrunn, Agnes (2008) Selective agonism in somatostatin receptor signaling and regulation. Mol Cell Endocrinol 286:35-9

Showing the most recent 10 out of 47 publications