Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK032303-14
Application #
2138796
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1983-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Georgia
Department
Microbiology/Immun/Virology
Type
Schools of Arts and Sciences
DUNS #
City
Athens
State
GA
Country
United States
Zip Code
30602
Dailey, Harry A; Meissner, Peter N (2013) Erythroid heme biosynthesis and its disorders. Cold Spring Harb Perspect Med 3:a011676
Medlock, Amy E; Najahi-Missaoui, Wided; Ross, Teresa A et al. (2012) Identification and characterization of solvent-filled channels in human ferrochelatase. Biochemistry 51:5422-33
Hamza, Iqbal; Dailey, Harry A (2012) One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans. Biochim Biophys Acta 1823:1617-32
Chen, Caiyong; Samuel, Tamika K; Sinclair, Jason et al. (2011) An intercellular heme-trafficking protein delivers maternal heme to the embryo during development in C. elegans. Cell 145:720-31
Dailey, Harry A; Septer, Alecia N; Daugherty, Lauren et al. (2011) The Escherichia coli protein YfeX functions as a porphyrinogen oxidase, not a heme dechelatase. MBio 2:e00248-11
Boynton, Tye O; Gerdes, Svetlana; Craven, Sarah H et al. (2011) Discovery of a gene involved in a third bacterial protoporphyrinogen oxidase activity through comparative genomic analysis and functional complementation. Appl Environ Microbiol 77:4795-801
Dailey, Tamara A; Boynton, Tye O; Albetel, Angela-Nadia et al. (2010) Discovery and Characterization of HemQ: an essential heme biosynthetic pathway component. J Biol Chem 285:25978-86
Chen, Wen; Dailey, Harry A; Paw, Barry H (2010) Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis. Blood 116:628-30
Boynton, Tye O; Daugherty, Lauren E; Dailey, Tamara A et al. (2009) Identification of Escherichia coli HemG as a novel, menadione-dependent flavodoxin with protoporphyrinogen oxidase activity. Biochemistry 48:6705-11
Shepherd, M; Dailey, H A (2009) Peroxidase activity of cytochrome C facilitates the protoporphyrinogen oxidase reaction. Cell Mol Biol (Noisy-le-grand) 55:6-14

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