Function and Regulation of Fatty Acid Binding Proteins

Bass, Nathan M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK032926-12
• Application #: 2138921
• Study Section: Metabolism Study Section (MET)
• Project Start: 1985-01-01
• Project End: 1998-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 12
• Fiscal Year: 1996

Institution

• Name: University of California San Francisco
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 073133571
• City: San Francisco
• State: CA
• Country: United States
• Zip Code: 94143

Publications

Kaikaus, R M; Chan, W K; Lysenko, N et al. (1993) Induction of peroxisomal fatty acid beta-oxidation and liver fatty acid-binding protein by peroxisome proliferators. Mediation via the cytochrome P-450IVA1 omega-hydroxylase pathway. J Biol Chem 268:9593-603

Kaikaus, R M; Sui, Z; Lysenko, N et al. (1993) Regulation of pathways of extramitochondrial fatty acid oxidation and liver fatty acid-binding protein by long-chain monocarboxylic fatty acids in hepatocytes. Effect of inhibition of carnitine palmitoyltransferase I. J Biol Chem 268:26866-71

Ockner, R K; Kaikaus, R M; Bass, N M (1993) Fatty-acid metabolism and the pathogenesis of hepatocellular carcinoma: review and hypothesis. Hepatology 18:669-76

Kaikaus, R M; Chan, W K; Ortiz de Montellano, P R et al. (1993) Mechanisms of regulation of liver fatty acid-binding protein. Mol Cell Biochem 123:93-100

Bass, N M (1993) Cellular binding proteins for fatty acids and retinoids: similar or specialized functions? Mol Cell Biochem 123:191-202

Schurer, N Y; Bass, N M; Jin, S et al. (1993) High-affinity fatty acid-binding activity in epidermis and cultured keratinocytes is attributable to high-molecular-weight and not low-molecular-weight fatty acid-binding proteins. J Invest Dermatol 100:82-6

Medzihradszky, K F; Gibson, B W; Kaur, S et al. (1992) The primary structure of fatty-acid-binding protein from nurse shark liver. Structural and evolutionary relationship to the mammalian fatty-acid-binding protein family. Eur J Biochem 203:327-39

Ortiz de Montellano, P R; Chan, W K; Tuck, S F et al. (1992) Mechanism-based probes of the topology and function of fatty acid hydroxylases. FASEB J 6:695-9

Ockner, R K; Kaikaus, R M; Bass, N M (1992) Fatty acid binding proteins: recent concepts of regulation and function. Prog Clin Biol Res 375:189-204

Bass, N M; Manning, J A; Luer, C A (1991) Isolation and characterization of fatty acid binding protein in the liver of the nurse shark, Ginglymostoma cirratum. Comp Biochem Physiol A Comp Physiol 98:355-62