Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK033727-12
Application #
2139145
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1985-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Black, D J; Halling, D Brent; Mandich, David V et al. (2005) Calmodulin interactions with IQ peptides from voltage-dependent calcium channels. Am J Physiol Cell Physiol 288:C669-76
Tang, Wei; Halling, D Brent; Black, D J et al. (2003) Apocalmodulin and Ca2+ calmodulin-binding sites on the CaV1.2 channel. Biophys J 85:1538-47
Van Lierop, Jacquelyn E; Wilson, David P; Davis, Jonathan P et al. (2002) Activation of smooth muscle myosin light chain kinase by calmodulin. Role of LYS(30) and GLY(40). J Biol Chem 277:6550-8
Davis, Jonathan P; Rall, Jack A; Reiser, Peter J et al. (2002) Engineering competitive magnesium binding into the first EF-hand of skeletal troponin C. J Biol Chem 277:49716-26
Tikunova, Svetlana B; Rall, Jack A; Davis, Jonathan P (2002) Effect of hydrophobic residue substitutions with glutamine on Ca(2+) binding and exchange with the N-domain of troponin C. Biochemistry 41:6697-705
Johnson, J David; Tikunova, Svetlana B (2002) Fluorescence methods for measuring calcium affinity and calcium exchange with proteins. Methods Mol Biol 173:89-102
Tikunova, S B; Black, D J; Johnson, J D et al. (2001) Modifying Mg2+ binding and exchange with the N-terminal of calmodulin. Biochemistry 40:3348-53
Adak, S; Santolini, J; Tikunova, S et al. (2001) Neuronal nitric-oxide synthase mutant (Ser-1412 --> Asp) demonstrates surprising connections between heme reduction, NO complex formation, and catalysis. J Biol Chem 276:1244-52
Black, D J; Tikunova, S B; Johnson, J D et al. (2000) Acid pairs increase the N-terminal Ca2+ affinity of CaM by increasing the rate of Ca2+ association. Biochemistry 39:13831-7
Lee, S H; Johnson, J D; Walsh, M P et al. (2000) Differential regulation of Ca2+/calmodulin-dependent enzymes by plant calmodulin isoforms and free Ca2+ concentration. Biochem J 350 Pt 1:299-306

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