Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK034738-03
Application #
3232982
Study Section
Metabolism Study Section (MET)
Project Start
1984-12-01
Project End
1987-11-30
Budget Start
1986-12-01
Budget End
1987-11-30
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
Pennsylvania State University
Department
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033

  Publications

Ananieva, Elitsa A; Van Horn, Cynthia G; Jones, Meghan R et al. (2017) Liver BCATm transgenic mouse model reveals the important role of the liver in maintaining BCAA homeostasis. J Nutr Biochem 40:132-140
Neishabouri, S Hallaj; Hutson, S M; Davoodi, J (2015) Chronic activation of mTOR complex 1 by branched chain amino acids and organ hypertrophy. Amino Acids 47:1167-82
Ananieva, Elitsa A; Patel, Chirag H; Drake, Charles H et al. (2014) Cytosolic branched chain aminotransferase (BCATc) regulates mTORC1 signaling and glycolytic metabolism in CD4+ T cells. J Biol Chem 289:18793-804
Brunetti-Pierri, Nicola; Lanpher, Brendan; Erez, Ayelet et al. (2011) Phenylbutyrate therapy for maple syrup urine disease. Hum Mol Genet 20:631-40
Islam, Mohammad Mainul; Nautiyal, Manisha; Wynn, R Max et al. (2010) Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm). J Biol Chem 285:265-76
Nautiyal, Manisha; Sweatt, Andrew J; MacKenzie, James A et al. (2010) Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system. Eur J Neurosci 32:560-9
Conway, Myra E; Coles, Steven J; Islam, Mohammad M et al. (2008) Regulatory control of human cytosolic branched-chain aminotransferase by oxidation and S-glutathionylation and its interactions with redox sensitive neuronal proteins. Biochemistry 47:5465-79
Islam, Mohammad Mainul; Wallin, Reidar; Wynn, R Max et al. (2007) A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex. J Biol Chem 282:11893-903
Garcia-Espinosa, Maria A; Wallin, Reidar; Hutson, Susan M et al. (2007) Widespread neuronal expression of branched-chain aminotransferase in the CNS: implications for leucine/glutamate metabolism and for signaling by amino acids. J Neurochem 100:1458-68
Yennawar, Neela H; Islam, Mohammad Mainul; Conway, Myra et al. (2006) Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. J Biol Chem 281:39660-71

Showing the most recent 10 out of 48 publications