Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK035385-06
Application #
3233697
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1985-07-01
Project End
1993-06-30
Budget Start
1989-12-01
Budget End
1990-06-30
Support Year
6
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Singh, Jagmohan; Mohanty, Ipsita; Rattan, Satish (2018) In vivo magnetofection: a novel approach for targeted topical delivery of nucleic acids for rectoanal motility disorders. Am J Physiol Gastrointest Liver Physiol 314:G109-G118
Mohanty, Ipsita; Parija, Subas Chandra; Suklabaidya, Sujit et al. (2018) Acidosis potentiates endothelium-dependent vasorelaxation and gap junction communication in the superior mesenteric artery. Eur J Pharmacol 827:22-31
Kumar, S; Singh, J; Rattan, S et al. (2017) Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. Aliment Pharmacol Ther 45:883-898
Rattan, Satish (2017) Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone. Am J Physiol Gastrointest Liver Physiol 312:G63-G66
Singh, Jagmohan; Mohanty, Ipsita; Addya, Sankar et al. (2017) Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone. Sci Rep 7:1477
Krishna, Chadalavada Vijay; Singh, Jagmohan; Thangavel, Chellappagounder et al. (2016) Role of microRNAs in gastrointestinal smooth muscle fibrosis and dysfunction: novel molecular perspectives on the pathophysiology and therapeutic targeting. Am J Physiol Gastrointest Liver Physiol 310:G449-59
Singh, Jagmohan; Boopathi, Ettickan; Addya, Sankar et al. (2016) Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. Am J Physiol Gastrointest Liver Physiol 311:G964-G973
Mandaliya, Rohan; Burkart, Ashlie L; DiMarino, Anthony J et al. (2016) Association between common variable immunodeficiency and collagenous infiltrative disorders of the gastrointestinal tract: A series of four patients. Indian J Gastroenterol 35:133-8
Kumar, Sumit; Singh, Jagmohan; Kedika, Ramalinga et al. (2016) Role of muscarinic-3 receptor antibody in systemic sclerosis: correlation with disease duration and effects of IVIG. Am J Physiol Gastrointest Liver Physiol 310:G1052-60
Mandaliya, Rohan; DiMarino, Anthony J; Moleski, Stephanie et al. (2015) Survey of anal sphincter dysfunction using anal manometry in patients with fecal incontinence: a possible guide to therapy. Ann Gastroenterol 28:469-74

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