Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK035527-12
Application #
2139587
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1985-09-30
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Missouri-Columbia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
112205955
City
Columbia
State
MO
Country
United States
Zip Code
65211
Fang, Yujiang; Sharp, Gordon C; Braley-Mullen, Helen (2011) Effect of transgenic overexpression of FLIP on lymphocytes on development and resolution of experimental autoimmune thyroiditis. Am J Pathol 179:1211-20
Fang, Yujiang; Chen, Kemin; Jackson, Daniel A et al. (2010) Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice. Immunology 129:329-37
Fang, Yujiang; Yu, Shiguang; Ellis, Jason S et al. (2010) Comparison of sensitivity of Th1, Th2, and Th17 cells to Fas-mediated apoptosis. J Leukoc Biol 87:1019-28
van der Voort, Robbert; Verweij, Viviènne; de Witte, Theo M et al. (2010) An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6+ cells. J Leukoc Biol 87:1029-39
Fang, Yujiang; Zhao, Lei; Yan, Feng (2010) Chemokines as novel therapeutic targets in autoimmune thyroiditis. Recent Pat DNA Gene Seq 4:52-7
Fang, Yujiang; Zhao, Lei; Parker, Charles A et al. (2010) Modulation of apoptosis: new opportunities for drug discovery to treat autoimmune thyroiditis. Recent Pat Inflamm Allergy Drug Discov 4:255-60
Fang, Y; Sharp, G C; Yagita, H et al. (2008) A critical role for TRAIL in resolution of granulomatous experimental autoimmune thyroiditis. J Pathol 216:505-13
Fang, Yujiang; Braley-Mullen, Helen (2008) Cultured murine thyroid epithelial cells expressing transgenic Fas-associated death domain-like interleukin-1beta converting enzyme inhibitory protein are protected from fas-mediated apoptosis. Endocrinology 149:3321-9
Fang, Yujiang; Sharp, Gordon C; Braley-Mullen, Helen (2008) Interleukin-10 promotes resolution of granulomatous experimental autoimmune thyroiditis. Am J Pathol 172:1591-602
Fang, Yujiang; DeMarco, Vincent G; Sharp, Gordon C et al. (2007) Expression of transgenic FLIP on thyroid epithelial cells inhibits induction and promotes resolution of granulomatous experimental autoimmune thyroiditis in CBA/J mice. Endocrinology 148:5734-45

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