Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK036870-12
Application #
2139901
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1985-07-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Biochemistry
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Obrochta, Kristin M; Krois, Charles R; Campos, Benito et al. (2015) Insulin regulates retinol dehydrogenase expression and all-trans-retinoic acid biosynthesis through FoxO1. J Biol Chem 290:7259-68
Obrochta, Kristin M; Kane, Maureen A; Napoli, Joseph L (2014) Effects of diet and strain on mouse serum and tissue retinoid concentrations. PLoS One 9:e99435
Chudnovskiy, Rostislav; Thompson, Airlia; Tharp, Kevin et al. (2014) Consumption of clarified grapefruit juice ameliorates high-fat diet induced insulin resistance and weight gain in mice. PLoS One 9:e108408
Ashique, Amir M; May, Scott R; Kane, Maureen A et al. (2012) Morphological defects in a novel Rdh10 mutant that has reduced retinoic acid biosynthesis and signaling. Genesis 50:415-23
Jiang, Weiya; Napoli, Joseph L (2012) Reorganization of cellular retinol-binding protein type 1 and lecithin:retinol acyltransferase during retinyl ester biosynthesis. Biochim Biophys Acta 1820:859-69
Napoli, Joseph L (2012) Physiological insights into all-trans-retinoic acid biosynthesis. Biochim Biophys Acta 1821:152-67
Wang, Chao; Kane, Maureen A; Napoli, Joseph L (2011) Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes. J Biol Chem 286:6542-53
Kane, Maureen A; Bright, Frank V; Napoli, Joseph L (2011) Binding affinities of CRBPI and CRBPII for 9-cis-retinoids. Biochim Biophys Acta 1810:514-8
Kane, Maureen A; Napoli, Joseph L (2010) Quantification of endogenous retinoids. Methods Mol Biol 652:1-54
Shih, Michelle Y S; Kane, Maureen A; Zhou, Ping et al. (2009) Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin. J Biol Chem 284:4292-9

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