Physiological Adaptation to Sustained Hypo-Osomolality

Verbalis, Joseph G.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK038094-08
• Application #: 2140271
• Study Section: Neurology A Study Section (NEUA)
• Program Officer: Scherbenske, M James
• Project Start: 1988-08-01
• Project End: 1997-12-31
• Budget Start: 1995-08-01
• Budget End: 1997-12-31
• Support Year: 8
• Fiscal Year: 1995

Institution

• Name: Georgetown University
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 049515844
• City: Washington
• State: DC
• Country: United States
• Zip Code: 20057

Publications

Hassan, Ali; Tian, Ying; Zheng, Wei et al. (2005) Small interfering RNA-mediated functional silencing of vasopressin V2 receptors in the mouse kidney. Physiol Genomics 21:382-8

Song, Jian; Hu, Xinqun; Khan, Osman et al. (2004) Increased blood pressure, aldosterone activity, and regional differences in renal ENaC protein during vasopressin escape. Am J Physiol Renal Physiol 287:F1076-83

Song, Jian; Knepper, Mark A; Hu, Xinqun et al. (2004) Rosiglitazone activates renal sodium- and water-reabsorptive pathways and lowers blood pressure in normal rats. J Pharmacol Exp Ther 308:426-33

Tian, Ying; Serino, Ryota; Verbalis, Joseph G (2004) Downregulation of renal vasopressin V2 receptor and aquaporin-2 expression parallels age-associated defects in urine concentration. Am J Physiol Renal Physiol 287:F797-805

Murase, Takashi; Tian, Ying; Fang, Xiao Ying et al. (2003) Synergistic effects of nitric oxide and prostaglandins on renal escape from vasopressin-induced antidiuresis. Am J Physiol Regul Integr Comp Physiol 284:R354-62

Song, Jian; Knepper, Mark A; Verbalis, Joseph G et al. (2003) Increased renal ENaC subunit and sodium transporter abundances in streptozotocin-induced type 1 diabetes. Am J Physiol Renal Physiol 285:F1125-37

Kitiyakara, Chagriya; Welch, William J; Verbalis, Joseph G et al. (2002) Role of thromboxane receptors in the dipsogenic response to central angiotensin II. Am J Physiol Regul Integr Comp Physiol 282:R865-9

Bickel, Crystal A; Knepper, Mark A; Verbalis, Joseph G et al. (2002) Dysregulation of renal salt and water transport proteins in diabetic Zucker rats. Kidney Int 61:2099-110

Bickel, C A; Verbalis, J G; Knepper, M A et al. (2001) Increased renal Na-K-ATPase, NCC, and beta-ENaC abundance in obese Zucker rats. Am J Physiol Renal Physiol 281:F639-48

Ecelbarger, C A; Knepper, M A; Verbalis, J G (2001) Increased abundance of distal sodium transporters in rat kidney during vasopressin escape. J Am Soc Nephrol 12:207-17