Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK038185-09
Application #
2140314
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1987-09-01
Project End
1996-11-30
Budget Start
1995-07-01
Budget End
1996-11-30
Support Year
9
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Tzortzaki, Eleni G; Yang, Min; Glass, Dayna et al. (2003) Impaired expression of an organic cation transporter, IMPT1, in a knockout mouse model for kidney stone disease. Urol Res 31:257-61
Liang, Li; Shao, Changshun; Deng, Li et al. (2002) Radiation-induced genetic instability in vivo depends on p53 status. Mutat Res 502:69-80
Tzortzaki, Eleni G; Glass, Dayna; Yang, Min et al. (2002) Gender- and age-dependent changes in kidney androgen protein mRNA expression in a knockout mouse model for nephrolithiasis. J Histochem Cytochem 50:1663-9
Shao, Changshun; Yin, Moying; Deng, Li et al. (2002) Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice. Oncogene 21:2840-5
Wang, Li; Raikwar, Nandita; Yang, Min et al. (2002) Induction of alpha-catenin, integrin alpha3, integrin beta6, and PDGF-B by 2,8-dihydroxyadenine crystals in cultured kidney epithelial cells. Exp Nephrol 10:365-73
Cervantes, Rachel B; Stringer, James R; Shao, Changshun et al. (2002) Embryonic stem cells and somatic cells differ in mutation frequency and type. Proc Natl Acad Sci U S A 99:3586-90
Degousee, Norbert; Ghomashchi, Farideh; Stefanski, Eva et al. (2002) Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis. J Biol Chem 277:5061-73
Evan, A P; Bledsoe, S B; Connors, B A et al. (2001) Sequential analysis of kidney stone formation in the Aprt knockout mouse. Kidney Int 60:910-23
Degousee, N; Stefanski, E; Lindsay, T F et al. (2001) p38 MAPK regulates group IIa phospholipase A2 expression in interleukin-1beta -stimulated rat neonatal cardiomyocytes. J Biol Chem 276:43842-9
Deng, L; Yang, M; Frund, S et al. (2001) 2,8-Dihydroxyadenine urolithiasis in a patient with considerable residual adenine phosphoribosyltransferase activity in cell extracts but with mutations in both copies of APRT. Mol Genet Metab 72:260-4

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