Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK038305-11
Application #
2140355
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1986-07-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Pathology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Dosch, Natalie C; Guslits, Elyssa F; Weber, Morgan B et al. (2016) Maternal Obesity Affects Inflammatory and Iron Indices in Umbilical Cord Blood. J Pediatr 172:20-8
Tafani, Marco; Karpinich, Natalie O; Serroni, Ada et al. (2006) Re-evaluation of the distinction between type I and type II cells: the necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon Fas receptor activation. J Cell Physiol 208:556-65
Karpinich, Natalie O; Tafani, Marco; Schneider, Timothy et al. (2006) The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax. J Cell Physiol 208:55-63
Tafani, Marco; Karpinich, Natalie O; Hurster, Kathryn A et al. (2002) Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition. J Biol Chem 277:10073-82
Karpinich, Natalie O; Tafani, Marco; Rothman, Ronald J et al. (2002) The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. J Biol Chem 277:16547-52
Tafani, Marco; Cohn, Joshua A; Karpinich, Natalie O et al. (2002) Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. J Biol Chem 277:49569-76
Tafani, M; Minchenko, D A; Serroni, A et al. (2001) Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine. Cancer Res 61:2459-66
Pastorino, J G; Tafani, M; Rothman, R J et al. (1999) Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. J Biol Chem 274:31734-9
Pastorino, J G; Tafani, M; Farber, J L (1999) Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway. J Biol Chem 274:19411-6
Pastorino, J G; Chen, S T; Tafani, M et al. (1998) The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J Biol Chem 273:7770-5

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