Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK038652-15
Application #
6380566
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Doo, Edward
Project Start
1987-07-01
Project End
2004-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
15
Fiscal Year
2001
Total Cost
$250,429
Indirect Cost
Name
Veterans Medical Research Fdn/San Diego
Department
Type
DUNS #
933863508
City
San Diego
State
CA
Country
United States
Zip Code
92161
Buck, Martina; Solis-Herruzo, Jose; Chojkier, Mario (2016) C/EBP?-Thr217 Phosphorylation Stimulates Macrophage Inflammasome Activation and Liver Injury. Sci Rep 6:24268
Buck, Martina; Garcia-Tsao, Guadalupe; Groszmann, Roberto J et al. (2014) Novel inflammatory biomarkers of portal pressure in compensated cirrhosis patients. Hepatology 59:1052-9
Chojkier, Mario; Elkhayat, Hisham; Sabry, Dina et al. (2012) Pioglitazone decreases hepatitis C viral load in overweight, treatment naïve, genotype 4 infected-patients: a pilot study. PLoS One 7:e31516
Buck, Martina; Chojkier, Mario (2011) C/EBP?-Thr217 phosphorylation signaling contributes to the development of lung injury and fibrosis in mice. PLoS One 6:e25497
Ramamoorthy, Sonia; Donohue, Michael; Buck, Martina (2009) Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. Am J Physiol Endocrinol Metab 297:E392-401
Feldstein, Ariel; Kleiner, David; Kravetz, David et al. (2009) Severe hepatocellular injury with apoptosis induced by a hepatitis C polymerase inhibitor. J Clin Gastroenterol 43:374-81
Buck, Martina (2008) Direct infection and replication of naturally occurring hepatitis C virus genotypes 1, 2, 3 and 4 in normal human hepatocyte cultures. PLoS One 3:e2660
Buck, Martina (2008) A novel domain of BRCA1 interacts with p53 in breast cancer cells. Cancer Lett 268:137-45
Buck, Martina (2008) Targeting ribosomal S-6 kinase for the prevention and treatment of liver injury and liver fibrosis. Drug News Perspect 21:301-6
Buck, Martina; Chojkier, Mario (2007) C/EBPbeta phosphorylation rescues macrophage dysfunction and apoptosis induced by anthrax lethal toxin. Am J Physiol Cell Physiol 293:C1788-96

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