Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK039298-02
Application #
3239073
Study Section
General Medicine B Study Section (GMB)
Project Start
1987-07-01
Project End
1990-06-30
Budget Start
1988-07-01
Budget End
1989-06-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Zacchia, Miriam; Tian, Xuefei; Zona, Enrica et al. (2018) Acid Stimulation of the Citrate Transporter NaDC-1 Requires Pyk2 and ERK1/2 Signaling Pathways. J Am Soc Nephrol 29:1720-1730
Liu, Liping; Zacchia, Miriam; Tian, Xuefei et al. (2010) Acid regulation of NaDC-1 requires a functional endothelin B receptor. Kidney Int 78:895-904
Zacchia, Miriam; Preisig, Patricia (2010) Low urinary citrate: an overview. J Nephrol 23 Suppl 16:S49-56
Preisig, P A (2007) The acid-activated signaling pathway: starting with Pyk2 and ending with increased NHE3 activity. Kidney Int 72:1324-9
Yang, Xiaojing; Huang, Hai-Chang; Yin, Helen et al. (2007) RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3. Am J Physiol Renal Physiol 293:F1054-64
Moe, Orson W; Preisig, Patricia A (2006) Dual role of citrate in mammalian urine. Curr Opin Nephrol Hypertens 15:419-24
Laghmani, Kamel; Sakamoto, Aiji; Yanagisawa, Masashi et al. (2005) A consensus sequence in the endothelin-B receptor second intracellular loop is required for NHE3 activation by endothelin-1. Am J Physiol Renal Physiol 288:F732-9
Alpern, Robert J; Preisig, Patricia A (2004) Dietary acid, endothelins, and sleep. Trans Am Clin Climatol Assoc 115:385-93; discussion 393-4
Li, Shaoying; Sato, Soichiro; Yang, Xiaojing et al. (2004) Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3. J Clin Invest 114:1782-9
Licht, Christoph; Laghmani, Kamel; Yanagisawa, Masashi et al. (2004) An autocrine role for endothelin-1 in the regulation of proximal tubule NHE3. Kidney Int 65:1320-6

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