Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK039520-09S1
Application #
655782
Study Section
Biochemistry Study Section (BIO)
Project Start
1988-02-01
Project End
1998-01-31
Budget Start
1995-02-01
Budget End
1996-01-31
Support Year
9
Fiscal Year
1995
Total Cost
Indirect Cost
Name
California Institute of Technology
Department
Type
Schools of Arts and Sciences
DUNS #
078731668
City
Pasadena
State
CA
Country
United States
Zip Code
91125
Kim, Jeong-Mok; Seok, Ok-Hee; Ju, Shinyeong et al. (2018) Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway. Science 362:
Chen, Shun-Jia; Wu, Xia; Wadas, Brandon et al. (2017) An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes. Science 355:
Oh, Jang-Hyun; Chen, Shun-Jia; Varshavsky, Alexander (2017) A reference-based protein degradation assay without global translation inhibitors. J Biol Chem 292:21457-21465
Oh, Jang-Hyun; Hyun, Ju-Yeon; Varshavsky, Alexander (2017) Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway. Proc Natl Acad Sci U S A 114:E4370-E4379
Wadas, Brandon; Piatkov, Konstantin I; Brower, Christopher S et al. (2016) Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays. J Biol Chem 291:20976-20992
Liu, Yu-Jiao; Liu, Chao; Chang, ZeNan et al. (2016) Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway. J Biol Chem 291:7426-38
Wadas, Brandon; Borjigin, Jimo; Huang, Zheping et al. (2016) Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway. J Biol Chem 291:17178-96
Piatkov, Konstantin I; Vu, Tri T M; Hwang, Cheol-Sang et al. (2015) Formyl-methionine as a degradation signal at the N-termini of bacterial proteins. Microb Cell 2:376-393
Park, Sang-Eun; Kim, Jeong-Mok; Seok, Ok-Hee et al. (2015) Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway. Science 347:1249-1252
Varshavsky, Alexander (2014) Discovery of the biology of the ubiquitin system. JAMA 311:1969-70

Showing the most recent 10 out of 74 publications