Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK039776-09A1
Application #
2141059
Study Section
Pathology A Study Section (PTHA)
Project Start
1987-09-30
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Kim, Il Young; Kim, Sang Soo; Lee, Hye Won et al. (2018) The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus. BMC Nephrol 19:248
Rhee, Harin; Han, Miyeun; Kim, Sang Soo et al. (2018) The expression of two isoforms of matrix metalloproteinase-2 in aged mouse models of diabetes mellitus and chronic kidney disease. Kidney Res Clin Pract 37:222-229
Baligand, Celine; Qin, Hecong; True-Yasaki, Aisha et al. (2017) Hyperpolarized 13 C magnetic resonance evaluation of renal ischemia reperfusion injury in a murine model. NMR Biomed 30:
Ceron, Carla S; Baligand, Celine; Joshi, Sunil et al. (2017) An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury. Am J Physiol Renal Physiol 312:F1166-F1183
Wanga, Shaynah; Ceron, Carla S; Delgado, Cynthia et al. (2015) Two Distinct Isoforms of Matrix Metalloproteinase-2 Are Associated with Human Delayed Kidney Graft Function. PLoS One 10:e0136276
Chintala, Hembindu; Liu, Haibo; Parmar, Rahul et al. (2012) Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene. J Biol Chem 287:40570-85
Mahimkar, Rajeev; Alfonso-Jaume, Maria Alejandra; Cape, Leslie M et al. (2011) Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype. Carcinogenesis 32:1806-14
Lovett, David H; Cheng, Sunfa; Cape, Leslie et al. (2010) YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis. Biochem Biophys Res Commun 398:482-8
Goldman, Shlomit; Lovett, David H; Shalev, Eliezer (2009) Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells. Reprod Biol Endocrinol 7:41
Cheng, Sunfa; Pollock, Allan S; Mahimkar, Rajeev et al. (2006) Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury. FASEB J 20:1898-900

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