Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK041004-07
Application #
2141571
Study Section
Special Emphasis Panel (ZRG4-GMA-1 (01))
Project Start
1989-08-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Boudry, Gaëlle; Hamilton, M Kristina; Chichlowski, Maciej et al. (2017) Bovine milk oligosaccharides decrease gut permeability and improve inflammation and microbial dysbiosis in diet-induced obese mice. J Dairy Sci 100:2471-2481
Hamilton, M Kristina; Ronveaux, Charlotte C; Rust, Bret M et al. (2017) Prebiotic milk oligosaccharides prevent development of obese phenotype, impairment of gut permeability, and microbial dysbiosis in high fat-fed mice. Am J Physiol Gastrointest Liver Physiol 312:G474-G487
Hamilton, M K; Raybould, H E (2016) Bugs, guts and brains, and the regulation of food intake and body weight. Int J Obes Suppl 6:S8-S14
Ronveaux, Charlotte C; Tomé, Daniel; Raybould, Helen E (2015) Glucagon-like peptide 1 interacts with ghrelin and leptin to regulate glucose metabolism and food intake through vagal afferent neuron signaling. J Nutr 145:672-80
de La Serre, Claire B; de Lartigue, Guillaume; Raybould, Helen E (2015) Chronic exposure to low dose bacterial lipopolysaccharide inhibits leptin signaling in vagal afferent neurons. Physiol Behav 139:188-94
Ronveaux, Charlotte C; de Lartigue, Guillaume; Raybould, Helen E (2014) Ability of GLP-1 to decrease food intake is dependent on nutritional status. Physiol Behav 135:222-9
de Lartigue, Guillaume; Ronveaux, Charlotte C; Raybould, Helen E (2014) Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity. Mol Metab 3:595-607
Eisner, Friederike; Martin, Elizabeth M; Küper, Markus A et al. (2013) CCK1-receptor stimulation protects against gut mediator-induced lung damage during endotoxemia. Cell Physiol Biochem 32:1878-90
de Lartigue, Guillaume; Barbier de la Serre, Claire; Espero, Elvis et al. (2012) Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats. PLoS One 7:e32967
de Lartigue, Guillaume; Barbier de la Serre, Claire; Espero, Elvis et al. (2011) Diet-induced obesity leads to the development of leptin resistance in vagal afferent neurons. Am J Physiol Endocrinol Metab 301:E187-95

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