Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK043743-06A1
Application #
2143241
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1991-06-15
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Cheng, Zhuan-Fen; Pai, Reetesh K; Cartwright, Christine A (2018) Rack1 function in intestinal epithelia: regulating crypt cell proliferation and regeneration and promoting differentiation and apoptosis. Am J Physiol Gastrointest Liver Physiol 314:G1-G13
Cheng, Zhuan-Fen; Cartwright, Christine A (2018) Rack1 maintains intestinal homeostasis by protecting the integrity of the epithelial barrier. Am J Physiol Gastrointest Liver Physiol 314:G263-G274
Swaminathan, G; Cartwright, C A (2012) Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis. Oncogene 31:376-89
Mamidipudi, V; Cartwright, C A (2009) A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. Oncogene 28:4421-33
Mamidipudi, Vidya; Miller, Laura D; Mochly-Rosen, Daria et al. (2007) Peptide modulators of Src activity in G1 regulate entry into S phase and proliferation of NIH 3T3 cells. Biochem Biophys Res Commun 352:423-30
Miller, Laura D; Lee, Kelly C; Mochly-Rosen, Daria et al. (2004) RACK1 regulates Src-mediated Sam68 and p190RhoGAP signaling. Oncogene 23:5682-6
Mamidipudi, Vidya; Chang, Betty Y; Harte, Rachel A et al. (2004) RACK1 inhibits the serum- and anchorage-independent growth of v-Src transformed cells. FEBS Lett 567:321-6
Chang, Betty Y; Cartwright, Christine A (2003) Detection of protein kinase-binding partners by the yeast two-hybrid analysis. Methods Mol Biol 233:327-43
Chang, Betty Y; Harte, Rachel A; Cartwright, Christine A (2002) RACK1: a novel substrate for the Src protein-tyrosine kinase. Oncogene 21:7619-29
Chang, B Y; Chiang, M; Cartwright, C A (2001) The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1. J Biol Chem 276:20346-56

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