Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK044319-08
Application #
6052648
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Hamilton, Frank A
Project Start
1992-09-30
Project End
2004-11-30
Budget Start
2000-03-01
Budget End
2000-11-30
Support Year
8
Fiscal Year
2000
Total Cost
$413,909
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Iyer, Shankar S; Gensollen, Thomas; Gandhi, Amit et al. (2018) Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses. Cell 173:1123-1134.e11
Aden, Konrad; Tran, Florian; Ito, Go et al. (2018) ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING. J Exp Med 215:2868-2886
Clancy-Thompson, Eleanor; Ali, Lestat; Bruck, Patrick T et al. (2018) IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells. Cancer Immunol Res 6:25-35
Schrumpf, Elisabeth; Kummen, Martin; Valestrand, Laura et al. (2017) The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation. J Hepatol 66:382-389
Schrumpf, Elisabeth; Jiang, Xiaojun; Zeissig, Sebastian et al. (2017) The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation. Physiol Rep 5:
Tschurtschenthaler, Markus; Adolph, Timon E; Ashcroft, Jonathan W et al. (2017) Defective ATG16L1-mediated removal of IRE1? drives Crohn's disease-like ileitis. J Exp Med 214:401-422
Kaser, Arthur; Blumberg, Richard S (2017) The road to Crohn's disease. Science 357:976-977
Zeissig, Sebastian; Peuker, Kenneth; Iyer, Shankar et al. (2017) CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation. Proc Natl Acad Sci U S A 114:10449-10454
Hosomi, Shuhei; Grootjans, Joep; Tschurtschenthaler, Markus et al. (2017) Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation. J Exp Med 214:2985-2997
Kim, Walter M; Kaser, Arthur; Blumberg, Richard S (2017) A role for oncostatin M in inflammatory bowel disease. Nat Med 23:535-536

Showing the most recent 10 out of 171 publications