Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK044510-04
Application #
2143848
Study Section
Nutrition Study Section (NTN)
Project Start
1992-02-01
Project End
2000-01-31
Budget Start
1996-02-15
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Louisiana State University Hsc Shreveport
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Shreveport
State
LA
Country
United States
Zip Code
71103
Circu, Magdalena L; Maloney, Ronald E; Aw, Tak Yee (2017) Low glucose stress decreases cellular NADH and mitochondrial ATP in colonic epithelial cancer cells: Influence of mitochondrial substrates. Chem Biol Interact 264:16-24
Wang, Bin; Aw, Tak Yee; Stokes, Karen Y (2016) The protection conferred against ischemia-reperfusion injury in the diabetic brain by N-acetylcysteine is associated with decreased dicarbonyl stress. Free Radic Biol Med 96:89-98
Li, Wei; Maloney, Ronald E; Aw, Tak Yee (2015) High glucose, glucose fluctuation and carbonyl stress enhance brain microvascular endothelial barrier dysfunction: Implications for diabetic cerebral microvasculature. Redox Biol 5:80-90
Busu, C; Atanasiu, V; Caldito, G et al. (2014) Influence of GSH synthesis inhibition on temporal distribution of NAD+/NADH during vascular endothelial cells proliferation. J Med Life 7:611-8
Xia, Hui; Mathew, Bobby; John, Tom et al. (2013) Microfluidic based immunosensor for detection and purification of carbonylated proteins. Biomed Microdevices 15:519-30
Bu?u, Carmina; Li, Wei; Caldito, Gloria et al. (2013) Inhibition of glutathione synthesis in brain endothelial cells lengthens S-phase transit time in the cell cycle: Implications for proliferation in recovery from oxidative stress and endothelial cell damage. Redox Biol 1:131-139
Li, Wei; Maloney, Ronald E; Circu, Magdalena L et al. (2013) Acute carbonyl stress induces occludin glycation and brain microvascular endothelial barrier dysfunction: role for glutathione-dependent metabolism of methylglyoxal. Free Radic Biol Med 54:51-61
Circu, Magdalena L; Aw, Tak Yee (2012) Intestinal redox biology and oxidative stress. Semin Cell Dev Biol 23:729-37
Xia, Hui; Murray, Kermit; Soper, Steven et al. (2012) Ultra sensitive affinity chromatography on avidin-functionalized PMMA microchip for low abundant post-translational modified protein enrichment. Biomed Microdevices 14:67-81
Circu, Magdalena L; Aw, Tak Yee (2012) Glutathione and modulation of cell apoptosis. Biochim Biophys Acta 1823:1767-77

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