Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044525-04
Application #
2143871
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1993-05-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Genetics
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Mathur, Priya S; Gierut, Jessica J; Guzman, Grace et al. (2016) Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer. Mol Cancer Res 14:563-73
Hart, Peter C; Ratti, Bianca A; Mao, Mao et al. (2016) Caveolin-1 regulates cancer cell metabolism via scavenging Nrf2 and suppressing MnSOD-driven glycolysis. Oncotarget 7:308-22
Peng, M; Ball-Kell, S M; Tyner, A L (2015) Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse. Cell Death Dis 6:e1848
Patel, Priyank; Asbach, Benedikt; Shteyn, Elina et al. (2015) Brk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4. Mol Cell Biol 35:1506-22
Chastkofsky, Michael I; Bie, Wenjun; Ball-Kell, Susan M et al. (2015) Protein Tyrosine Kinase 6 Regulates UVB-Induced Signaling and Tumorigenesis in Mouse Skin. J Invest Dermatol 135:2492-2501
Peng, Maoyu; Emmadi, Rajyasree; Wang, Zebin et al. (2014) PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors. Oncotarget 5:6038-48
Wang, Zebin; Zheng, Yu; Park, Hyun Jung et al. (2013) Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma. Mol Cancer Ther 12:759-67
Zheng, Yu; Tyner, Angela L (2013) Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer. Eur J Clin Invest 43:397-404
Zheng, Yu; Wang, Zebin; Bie, Wenjun et al. (2013) PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer. Cancer Res 73:5426-37
Peng, M; Ball-Kell, S M; Franks, R R et al. (2013) Protein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models. Oncogenesis 2:e81

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