Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044730-05
Application #
2143996
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1992-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Florida Institute of Technology
Department
Type
Other Domestic Higher Education
DUNS #
City
Melbourne
State
FL
Country
United States
Zip Code
32901
Jacobo, Sheila H; Chang, Chih-Tsung; Lee, Gue-Jae et al. (2006) Total synthesis of 8,12-iso-iPF3alpha-VI, an EPA-derived isoprostane: stereoselective introduction of the fifth asymmetric center. J Org Chem 71:1370-9
Kim, Seongjin; Bellone, Sophie; Maxey, Kirk M et al. (2005) Synthesis of 15R-PGD2: a potential DP2 receptor agonist. Bioorg Med Chem Lett 15:1873-6
Monneret, Guillaume; Boumiza, Radhia; Gravel, Sylvie et al. (2005) Effects of prostaglandin D(2) and 5-lipoxygenase products on the expression of CD203c and CD11b by basophils. J Pharmacol Exp Ther 312:627-34
Kim, Seongjin; Powell, William S; Lawson, John A et al. (2005) iPF2alpha-III-17,18,19,20-d4: total synthesis and metabolism. Bioorg Med Chem Lett 15:1613-7
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Polidori, M Cristina; Pratico, Domenico; Savino, Ketty et al. (2004) Increased F2 isoprostane plasma levels in patients with congestive heart failure are correlated with antioxidant status and disease severity. J Card Fail 10:334-8
Mercier, Frederic; Morin, Caroline; Cloutier, Martin et al. (2004) 5-Oxo-ETE regulates tone of guinea pig airway smooth muscle via activation of Ca2+ pools and Rho-kinase pathway. Am J Physiol Lung Cell Mol Physiol 287:L631-40
Rokach, Joshua; Kim, Seongjin; Bellone, Sophie et al. (2004) Total synthesis of isoprostanes: discovery and quantitation in biological systems. Chem Phys Lipids 128:35-56
Stamatiou, Panagiota B; Chan, Chi-Chung; Monneret, Guillaume et al. (2004) 5-oxo-6,8,11,14-eicosatetraenoic acid stimulates the release of the eosinophil survival factor granulocyte/macrophage colony-stimulating factor from monocytes. J Biol Chem 279:28159-64
Pratico, Domenico; Rokach, Joshua; Lawson, John et al. (2004) F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases. Chem Phys Lipids 128:165-71

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