Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK045228-13
Application #
6692973
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Program Officer
Malozowski, Saul N
Project Start
1992-02-01
Project End
2007-01-31
Budget Start
2004-02-01
Budget End
2005-01-31
Support Year
13
Fiscal Year
2004
Total Cost
$323,730
Indirect Cost

  Institution

Name
Yale University
Department
Veterinary Sciences
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Yao, Gang-Qing; Troiano, Nancy; Simpson, Christine A et al. (2017) Selective deletion of the soluble Colony-Stimulating Factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice. Bone Res 5:17022
Zhu, Meiling; Sun, Ben-Hua; Saar, Katarzyna et al. (2016) Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo. J Bone Miner Res 31:864-73
Yao, Chen; Yao, Gang-Qing; Sun, Ben-Hua et al. (2014) The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis. J Biol Chem 289:6775-90
Kawano, Tsutomu; Zhu, Meiling; Troiano, Nancy et al. (2013) LIM kinase 1 deficient mice have reduced bone mass. Bone 52:70-82
Itokowa, Takashi; Zhu, Mei-ling; Troiano, Nancy et al. (2011) Osteoclasts lacking Rac2 have defective chemotaxis and resorptive activity. Calcif Tissue Int 88:75-86
Yao, Gang-Qing; Wu, Jian-Jun; Troiano, Nancy et al. (2011) Targeted overexpression of Dkk1 in osteoblasts reduces bone mass but does not impair the anabolic response to intermittent PTH treatment in mice. J Bone Miner Metab 29:141-8
Kukreja, Anjli; Radfar, Soroosh; Sun, Ben-Hua et al. (2009) Dominant role of CD47-thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: implications for bone disease. Blood 114:3413-21
Williams, Bart O; Insogna, Karl L (2009) Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone. J Bone Miner Res 24:171-8
Yao, Gang-Qing; Wu, Jian-Jun; Ovadia, Shira et al. (2009) Targeted overexpression of the two colony-stimulating factor-1 isoforms in osteoblasts differentially affects bone loss in ovariectomized mice. Am J Physiol Endocrinol Metab 296:E714-20
Yu, Kuan-ping; Itokawa, Takashi; Zhu, Mei-ling et al. (2007) Breast cancer-associated gene 3 (BCA3) is a novel Rac1-interacting protein. J Bone Miner Res 22:628-37

Showing the most recent 10 out of 24 publications