Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK046207-10A1
Application #
2016637
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1992-07-15
Project End
1997-08-31
Budget Start
1997-05-15
Budget End
1997-08-31
Support Year
10
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Baylor College of Medicine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Carbonaro, Denise A; Jin, Xiangyang; Cotoi, Daniel et al. (2008) Neonatal bone marrow transplantation of ADA-deficient SCID mice results in immunologic reconstitution despite low levels of engraftment and an absence of selective donor T lymphoid expansion. Blood 111:5745-54
Mi, Tiejuan; Abbasi, Shahrzad; Zhang, Hong et al. (2008) Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling. J Clin Invest 118:1491-501
Mohsenin, Amir; Mi, Tiejuan; Xia, Yang et al. (2007) Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice. Am J Physiol Lung Cell Mol Physiol 293:L753-61
Schaubach, B M; Wen, H Y; Kellems, R E (2006) Regulation of murine Ada gene expression in the placenta by transcription factor RUNX1. Placenta 27:269-77
Carbonaro, Denise A; Jin, Xiangyang; Petersen, Denise et al. (2006) In vivo transduction by intravenous injection of a lentiviral vector expressing human ADA into neonatal ADA gene knockout mice: a novel form of enzyme replacement therapy for ADA deficiency. Mol Ther 13:1110-20
Chunn, Janci L; Mohsenin, Amir; Young, Hays W J et al. (2006) Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations. Am J Physiol Lung Cell Mol Physiol 290:L579-87
Chunn, Janci L; Molina, Jose G; Mi, Tiejuan et al. (2005) Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice. J Immunol 175:1937-46
Blackburn, Michael R; Kellems, Rodney E (2005) Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation. Adv Immunol 86:1-41
Aldrich, Melissa B; Chen, Wilma; Blackburn, Michael R et al. (2003) Impaired germinal center maturation in adenosine deaminase deficiency. J Immunol 171:5562-70
Morales, Julio C; Xia, Zhenfang; Lu, Tao et al. (2003) Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J Biol Chem 278:14971-7

Showing the most recent 10 out of 30 publications