Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK046868-03
Application #
2146136
Study Section
Endocrinology Study Section (END)
Project Start
1994-06-01
Project End
1999-05-31
Budget Start
1996-07-24
Budget End
1997-05-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Roof, Allyson K; Trudeau, Tammy; Gutierrez-Hartmann, Arthur (2018) Pituitary somatolactotropes evade an oncogenic response to Ras. Mol Cell Endocrinol 476:165-172
Roof, Allyson K; Jirawatnotai, Siwanon; Trudeau, Tammy et al. (2018) The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine. Endocrinology 159:2421-2434
Booth, Allyson; Trudeau, Tammy; Gomez, Crystal et al. (2014) Persistent ERK/MAPK activation promotes lactotrope differentiation and diminishes tumorigenic phenotype. Mol Endocrinol 28:1999-2011
Jean, Annie; Gutierrez-Hartmann, Arthur; Duval, Dawn L (2010) A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin gene promoter. Mol Endocrinol 24:91-103
Jedlicka, Paul; Sui, Xiaomei; Gutierrez-Hartmann, Arthur (2009) The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice. BMC Cancer 9:197
Jedlicka, Paul; Sui, Xiaomei; Sussel, Lori et al. (2009) Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine. Am J Pathol 174:1280-90
Gutierrez-Hartmann, Arthur; Duval, Dawn L; Bradford, Andrew P (2007) ETS transcription factors in endocrine systems. Trends Endocrinol Metab 18:150-8
Ferry, A L; Locasto, D M; Meszaros, L B et al. (2005) Pit-1beta reduces transcription and CREB-binding protein recruitment in a DNA context-dependent manner. J Endocrinol 185:173-85
Schweppe, Rebecca E; Melton, Alexis A; Brodsky, Kelley S et al. (2003) Purification and mass spectrometric identification of GA-binding protein (GABP) as the functional pituitary Ets factor binding to the basal transcription element of the prolactin promoter. J Biol Chem 278:16863-72
Duval, Dawn L; Jean, Annie; Gutierrez-Hartmann, Arthur (2003) Ras signaling and transcriptional synergy at a flexible Ets-1/Pit-1 composite DNA element is defined by the assembly of selective activation domains. J Biol Chem 278:39684-96

Showing the most recent 10 out of 22 publications