Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK047208-03
Application #
2146565
Study Section
Biopsychology Study Section (BPO)
Project Start
1994-08-20
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Blouet, Clémence; Schwartz, Gary J (2011) Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice. J Neurosci 31:6019-27
Fu, Jin; Dipatrizio, Nicholas V; Guijarro, Ana et al. (2011) Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine. J Neurosci 31:5730-6
Schwartz, Gary J (2011) Gut fat sensing in the negative feedback control of energy balance--recent advances. Physiol Behav 104:621-3
Iqbal, Jahangir; Li, Xiaosong; Chang, Benny Hung-Junn et al. (2010) An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption. J Lipid Res 51:1929-42
Nagajyothi, Fnu; Zhao, Dazhi; Machado, Fabiana S et al. (2010) Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection. J Infect Dis 202:1104-13
Schwartz, Gary J (2010) Brainstem integrative function in the central nervous system control of food intake. Forum Nutr 63:141-51
Ross, R A; Rossetti, L; Lam, T K T et al. (2010) Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production. Am J Physiol Endocrinol Metab 299:E633-9
Blouet, Clemence; Schwartz, Gary J (2010) Hypothalamic nutrient sensing in the control of energy homeostasis. Behav Brain Res 209:1-12
Schwartz, Gary J (2009) Your brain on fat: dietary-induced obesity impairs central nutrient sensing. Am J Physiol Endocrinol Metab 296:E967-8
Blouet, Clémence; Jo, Young-Hwan; Li, Xiaosong et al. (2009) Mediobasal hypothalamic leucine sensing regulates food intake through activation of a hypothalamus-brainstem circuit. J Neurosci 29:8302-11

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