Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK048105-03
Application #
2148185
Study Section
General Medicine B Study Section (GMB)
Project Start
1994-04-01
Project End
1998-08-31
Budget Start
1996-04-01
Budget End
1998-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Desir, Gary V (2009) Regulation of blood pressure and cardiovascular function by renalase. Kidney Int 76:366-70
Li, Guoyong; Xu, Jianchao; Wang, Peili et al. (2008) Catecholamines regulate the activity, secretion, and synthesis of renalase. Circulation 117:1277-82
Desir, Gary V (2008) Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease. Curr Opin Nephrol Hypertens 17:181-5
Li, Yanyan; Wang, Peili; Xu, Jianchao et al. (2007) Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII. Biochem Biophys Res Commun 362:658-64
Li, Yanyan; Wang, Peili; Xu, Jianchao et al. (2006) Voltage-gated potassium channel Kv1.3 regulates GLUT4 trafficking to the plasma membrane via a Ca2+-dependent mechanism. Am J Physiol Cell Physiol 290:C345-51
Hebert, Steven C; Desir, Gary; Giebisch, Gerhard et al. (2005) Molecular diversity and regulation of renal potassium channels. Physiol Rev 85:319-71
Xu, Jianchao; Li, Guoyong; Wang, Peili et al. (2005) Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure. J Clin Invest 115:1275-80
Xu, Jianchao; Wang, Peili; Li, Yanyan et al. (2004) The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity. Proc Natl Acad Sci U S A 101:3112-7
Tian, Shulan; Liu, Weimin; Wu, Yanling et al. (2002) Regulation of the voltage-gated K+ channel KCNA10 by KCNA4B, a novel beta-subunit. Am J Physiol Renal Physiol 283:F142-9
Segal, Alan S; Hayslett, John P; Desir, Gary V (2002) On the natriuretic effect of verapamil: inhibition of ENaC and transepithelial sodium transport. Am J Physiol Renal Physiol 283:F765-70

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