Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK050277-10S1
Application #
6946084
Study Section
Skeletal Muscle and Exercise Physiology Study Section (SMEP)
Program Officer
Laughlin, Maren R
Project Start
1995-07-01
Project End
2008-05-31
Budget Start
2004-07-01
Budget End
2005-05-31
Support Year
10
Fiscal Year
2004
Total Cost
$43,790
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Physiology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Hughey, Curtis C; Trefts, Elijah; Bracy, Deanna P et al. (2018) Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. J Biol Chem 293:11944-11954
Wasserman, David H; Wang, Thomas J; Brown, Nancy J (2018) The Vasculature in Prediabetes. Circ Res 122:1135-1150
Hughey, Curtis C; James, Freyja D; Bracy, Deanna P et al. (2017) Loss of hepatic AMP-activated protein kinase impedes the rate of glycogenolysis but not gluconeogenic fluxes in exercising mice. J Biol Chem 292:20125-20140
Trefts, Elijah; Gannon, Maureen; Wasserman, David H (2017) The liver. Curr Biol 27:R1147-R1151
Lantier, Louise; Williams, Ashley S; Williams, Ian M et al. (2015) SIRT3 Is Crucial for Maintaining Skeletal Muscle Insulin Action and Protects Against Severe Insulin Resistance in High-Fat-Fed Mice. Diabetes 64:3081-92
Williams, Ashley S; Kang, Li; Wasserman, David H (2015) The extracellular matrix and insulin resistance. Trends Endocrinol Metab 26:357-66
Hughey, Curtis C; Wasserman, David H; Lee-Young, Robert S et al. (2014) Approach to assessing determinants of glucose homeostasis in the conscious mouse. Mamm Genome 25:522-38
Wu, Lan; Parekh, Vrajesh V; Gabriel, Curtis L et al. (2012) Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. Proc Natl Acad Sci U S A 109:E1143-52
Berglund, Eric D; Li, Candice Y; Ayala, Julio E et al. (2012) Regulation of endogenous glucose production in glucose transporter 4 over-expressing mice. PLoS One 7:e52355
Burmeister, M A; Bracy, D P; James, F D et al. (2012) Regulation of glucose kinetics during exercise by the glucagon-like peptide-1 receptor. J Physiol 590:5245-55

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