Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK050422-02
Application #
2151432
Study Section
Special Emphasis Panel (ZRG4-NTN (06))
Project Start
1995-09-30
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
De Franceschi, Lucia; Biondani, Andrea; Carta, Franco et al. (2008) PTPepsilon has a critical role in signaling transduction pathways and phosphoprotein network topology in red cells. Proteomics 8:4695-708
De Franceschi, Lucia; Daraio, Filomena; Filippini, Alida et al. (2006) Liver expression of hepcidin and other iron genes in two mouse models of beta-thalassemia. Haematologica 91:1336-42
Rivera, Alicia; De Franceschi, Lucia; Peters, Luanne L et al. (2006) Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes. Am J Physiol Cell Physiol 291:C880-6
De Franceschi, Lucia; Villa-Moruzzi, Emma; Biondani, Andrea et al. (2006) Regulation of K-Cl cotransport by protein phosphatase 1alpha in mouse erythrocytes. Pflugers Arch 451:760-8
Rivera, Alicia; Ferreira, Ana; Bertoni, Danielle et al. (2005) Abnormal regulation of Mg2+ transport via Na/Mg exchanger in sickle erythrocytes. Blood 105:382-6
Mallozzi, Cinzia; De Franceschi, Lucia; Brugnara, Carlo et al. (2005) Protein phosphatase 1alpha is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr. Free Radic Biol Med 38:1625-36
De Franceschi, Lucia; Rivera, Alicia; Fleming, Mark D et al. (2005) Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis. Blood 106:1454-9
de Franceschi, Lucia; Turrini, Franco; Honczarenko, Marek et al. (2004) In vivo reduction of erythrocyte oxidant stress in a murine model of beta-thalassemia. Haematologica 89:1287-98
Begenisich, Ted; Nakamoto, Tesuji; Ovitt, Catherine E et al. (2004) Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4. J Biol Chem 279:47681-7
De Franceschi, L; Olivieri, O; Corrocher, R (2004) Erythrocyte aging in neurodegenerative disorders. Cell Mol Biol (Noisy-le-grand) 50:179-85

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