Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK051563-01
Application #
2152617
Study Section
Endocrinology Study Section (END)
Project Start
1996-07-25
Project End
2000-06-30
Budget Start
1996-07-25
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Physiology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Cawthorn, William P; Scheller, Erica L; MacDougald, Ormond A (2012) Adipose tissue stem cells meet preadipocyte commitment: going back to the future. J Lipid Res 53:227-46
Cawthorn, William P; Scheller, Erica L; MacDougald, Ormond A (2012) Adipose tissue stem cells: the great WAT hope. Trends Endocrinol Metab 23:270-7
Cawthorn, William P; Bree, Adam J; Yao, Yao et al. (2012) Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a ?-catenin-dependent mechanism. Bone 50:477-89
Mori, Hiroyuki; Prestwich, Tyler C; Reid, Michael A et al. (2012) Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition. J Clin Invest 122:2405-16
Akhmetshina, Alfiya; Palumbo, Katrin; Dees, Clara et al. (2012) Activation of canonical Wnt signalling is required for TGF-?-mediated fibrosis. Nat Commun 3:735
Bommer, Guido T; MacDougald, Ormond A (2011) Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus. Cell Metab 13:241-7
Susperreguy, Sebastián; Prendes, Luciana P; Desbats, María A et al. (2011) Visualization by BiFC of different C/EBP? dimers and their interaction with HP1? reveals a differential subnuclear distribution of complexes in living cells. Exp Cell Res 317:706-23
Wei, Jun; Melichian, Denisa; Komura, Kazuhiro et al. (2011) Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum 63:1707-17
Wen, Xin; Cawthorn, William P; MacDougald, Ormond A et al. (2011) The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression. Biomaterials 32:6478-86
Clark, Anna M; Sousa, Kyle M; Chisolm, Claire N et al. (2010) Reversibly sealed multilayer microfluidic device for integrated cell perfusion and on-line chemical analysis of cultured adipocyte secretions. Anal Bioanal Chem 397:2939-47

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