Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK053347-06
Application #
6692240
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Hamilton, Frank A
Project Start
1998-08-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
6
Fiscal Year
2004
Total Cost
$289,200
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Ellermann, Melissa; Sartor, R Balfour (2018) Intestinal bacterial biofilms modulate mucosal immune responses. J Immunol Sci 2:13-18
Ho, G-T; Aird, R E; Liu, B et al. (2018) MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation. Mucosal Immunol 11:120-130
Ellermann, Melissa; Huh, Eun Young; Liu, Bo et al. (2015) Adherent-Invasive Escherichia coli Production of Cellulose Influences Iron-Induced Bacterial Aggregation, Phagocytosis, and Induction of Colitis. Infect Immun 83:4068-80
Goeser, Laura; Fan, Ting-Jia; Tchaptchet, Sandrine et al. (2015) Small heat-shock proteins, IbpAB, protect non-pathogenic Escherichia coli from killing by macrophage-derived reactive oxygen species. PLoS One 10:e0120249
Mishima, Yoshiyuki; Liu, Bo; Hansen, Jonathan J et al. (2015) Resident bacteria-stimulated IL-10-secreting B cells ameliorate T cell-mediated colitis by inducing Tr-1 cells that require IL-27-signaling. Cell Mol Gastroenterol Hepatol 1:295-310
Dogan, Belgin; Suzuki, Haruo; Herlekar, Deepali et al. (2014) Inflammation-associated adherent-invasive Escherichia coli are enriched in pathways for use of propanediol and iron and M-cell translocation. Inflamm Bowel Dis 20:1919-32
Shanahan, Michael T; Carroll, Ian M; Grossniklaus, Emily et al. (2014) Mouse Paneth cell antimicrobial function is independent of Nod2. Gut 63:903-10
Shanahan, Michael T; Carroll, Ian M; Gulati, Ajay S (2014) Critical design aspects involved in the study of Paneth cells and the intestinal microbiota. Gut Microbes 5:208-14
Eun, Chang Soo; Mishima, Yoshiyuki; Wohlgemuth, Steffen et al. (2014) Induction of bacterial antigen-specific colitis by a simplified human microbiota consortium in gnotobiotic interleukin-10-/- mice. Infect Immun 82:2239-46
Wuensch, Tilo; Ullrich, Sina; Schulz, Stephan et al. (2014) Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation. Inflamm Bowel Dis 20:671-84

Showing the most recent 10 out of 60 publications