Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK054084-03
Application #
2906244
Study Section
Special Emphasis Panel (ZRG4-GMB (05))
Program Officer
Rasooly, Rebekah S
Project Start
1997-09-20
Project End
2002-07-31
Budget Start
1999-08-01
Budget End
2000-07-31
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Henry Ford Health System
Department
Urology
Type
Schools of Medicine
DUNS #
073134603
City
Detroit
State
MI
Country
United States
Zip Code
48202
Koul, Sweaty; Khandrika, Lakshmipathi; Pshak, Thomas J et al. (2014) Oxalate upregulates expression of IL-2R? and activates IL-2R signaling in HK-2 cells, a line of human renal epithelial cells. Am J Physiol Renal Physiol 306:F1039-46
Pal, Mintu; Koul, Sweaty; Koul, Hari K (2013) The transcription factor sterile alpha motif (SAM) pointed domain-containing ETS transcription factor (SPDEF) is required for E-cadherin expression in prostate cancer cells. J Biol Chem 288:12222-31
Koul, Hari K; Pal, Mantu; Koul, Sweaty (2013) Role of p38 MAP Kinase Signal Transduction in Solid Tumors. Genes Cancer 4:342-59
Khandrika, Lakshmipathi; Koul, Sweaty; Meacham, Randall B et al. (2012) Kidney injury molecule-1 is up-regulated in renal epithelial cells in response to oxalate in vitro and in renal tissues in response to hyperoxaluria in vivo. PLoS One 7:e44174
Koul, Sweaty; Khandrika, Lakshmipathi; Meacham, Randall B et al. (2012) Genome wide analysis of differentially expressed genes in HK-2 cells, a line of human kidney epithelial cells in response to oxalate. PLoS One 7:e43886
Steffan, Joshua J; Koul, Sweaty; Meacham, Randall B et al. (2012) The transcription factor SPDEF suppresses prostate tumor metastasis. J Biol Chem 287:29968-78
Khandrika, L; Lieberman, R; Koul, S et al. (2009) Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1alpha levels contribute to emergence of an aggressive phenotype in prostate cancer. Oncogene 28:1248-60
Khandrika, Lakshmipathi; Kumar, Binod; Koul, Sweaty et al. (2009) Oxidative stress in prostate cancer. Cancer Lett 282:125-36
Myers, Jeremy B; Dall'era, Joseph E; Koul, Sweaty et al. (2009) Biochemical alterations in partial bladder outlet obstruction in mice: up-regulation of the mitogen activated protein kinase pathway. J Urol 181:1926-31
Khandrika, Lakshmipathi; Kim, Fernando J; Campagna, Adriano et al. (2008) Primary culture and characterization of human renal inner medullary collecting duct epithelial cells. J Urol 179:2057-63

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