Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK054111-03
Application #
2906246
Study Section
Nutrition Study Section (NTN)
Program Officer
May, Michael K
Project Start
1997-09-15
Project End
2000-08-31
Budget Start
1999-09-01
Budget End
2000-08-31
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of North Carolina Greensboro
Department
Administration
Type
Schools of Arts and Sciences
DUNS #
616152567
City
Greensboro
State
NC
Country
United States
Zip Code
27402
Fleet, James C (2017) The role of vitamin D in the endocrinology controlling calcium homeostasis. Mol Cell Endocrinol 453:36-45
DeSmet, Marsha L; Fleet, James C (2017) Constitutively active RAS signaling reduces 1,25 dihydroxyvitamin D-mediated gene transcription in intestinal epithelial cells by reducing vitamin D receptor expression. J Steroid Biochem Mol Biol 173:194-201
Reyes Fernandez, Perla C; Replogle, Rebecca A; Wang, Libo et al. (2016) Novel Genetic Loci Control Calcium Absorption and Femur Bone Mass as Well as Their Response to Low Calcium Intake in Male BXD Recombinant Inbred Mice. J Bone Miner Res 31:994-1002
Reyes-Fernandez, Perla C; Fleet, James C (2016) Compensatory Changes in Calcium Metabolism Accompany the Loss of Vitamin D Receptor (VDR) From the Distal Intestine and Kidney of Mice. J Bone Miner Res 31:143-51
Reyes-Fernandez, Perla C; Fleet, James C (2015) Luminal glucose does not enhance active intestinal calcium absorption in mice: evidence against a role for Ca(v)1.3 as a mediator of calcium uptake during absorption. Nutr Res 35:1009-15
Jiang, Yan; Fleet, James C (2012) Phorbol esters enhance 1?,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin D-24-hydroxylase (CYP24A1) gene expression through ERK-mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells. Mol Cell Endocrinol 361:31-9
Cui, Min; Li, Qiang; Johnson, Robert et al. (2012) Villin promoter-mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild-type and vitamin D receptor knockout mice. J Bone Miner Res 27:2097-107
Jiang, Yan; Fleet, James C (2012) Effect of phorbol 12-myristate 13-acetate activated signaling pathways on 1?, 25 dihydroxyvitamin D3 regulated human 25-hydroxyvitamin D3 24-hydroxylase gene expression in differentiated Caco-2 cells. J Cell Biochem 113:1599-607
Farrow, Emily G; Yu, Xijie; Summers, Lelia J et al. (2011) Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc Natl Acad Sci U S A 108:E1146-55
Adamec, Jiri; Jannasch, Amber; Huang, Jianjie et al. (2011) Development and optimization of an LC-MS/MS-based method for simultaneous quantification of vitamin D2 , vitamin D3 , 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3. J Sep Sci 34:11-20

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