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Spink, B C; Katz, B H; Hussain, M M et al. (2000) SULT1A1 catalyzes 2-methoxyestradiol sulfonation in MCF-7 breast cancer cells. Carcinogenesis 21:1947-57
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Spink, D C; Spink, B C; Zhuo, X et al. (2000) NADPH- and hydroperoxide-supported 17beta-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1. J Steroid Biochem Mol Biol 74:8-Nov
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Vakharia, D D; Gierthy, J F (2000) Use of a combined human liver microsome-estrogen receptor binding assay to assess potential estrogen modulating activity of PCB metabolites. Toxicol Lett 114:55-65
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Spink, B C; Fasco, M J; Gierthy, J F et al. (1998) 12-O-tetradecanoylphorbol-13-acetate upregulates the Ah receptor and differentially alters CYP1B1 and CYP1A1 expression in MCF-7 breast cancer cells. J Cell Biochem 70:289-96
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Spink, D C; Spink, B C; Cao, J Q et al. (1997) Induction of cytochrome P450 1B1 and catechol estrogen metabolism in ACHN human renal adenocarcinoma cells. J Steroid Biochem Mol Biol 62:223-32
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Gierthy, J F; Spink, B C; Figge, H L et al. (1996) Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 12-O-tetradecanoylphorbol-13-acetate and 17 beta-estradiol on estrogen receptor regulation in MCF-7 human breast cancer cells. J Cell Biochem 60:173-84
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DePasquale, J A; Samsonoff, W A; Gierthy, J F (1994) 17-beta-Estradiol induced alterations of cell-matrix and intercellular adhesions in a human mammary carcinoma cell line. J Cell Sci 107 ( Pt 5):1241-54
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Spink, D C; Hayes, C L; Young, N R et al. (1994) The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase. J Steroid Biochem Mol Biol 51:251-8
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Spink, D C; Johnson, J A; Connor, S P et al. (1994) Stimulation of 17 beta-estradiol metabolism in MCF-7 cells by bromochloro- and chloromethyl-substituted dibenzo-p-dioxins and dibenzofurans: correlations with antiestrogenic activity. J Toxicol Environ Health 41:451-66
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Gierthy, J F; Bennett, J A; Bradley, L M et al. (1993) Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Res 53:3149-53
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