Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES004090-09
Application #
2153555
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1991-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Suszkiw, Janusz B (2004) Presynaptic disruption of transmitter release by lead. Neurotoxicology 25:599-604
Sun, X; Tian, X; Tomsig, J L et al. (1999) Analysis of differential effects of Pb2+ on protein kinase C isozymes. Toxicol Appl Pharmacol 156:40-5
Tomsig, J L; Suszkiw, J B (1996) Metal selectivity of exocytosis in alpha-toxin-permeabilized bovine chromaffin cells. J Neurochem 66:644-50
Sun, L R; Suszkiw, J B (1995) Extracellular inhibition and intracellular enhancement of Ca2+ currents by Pb2+ in bovine adrenal chromaffin cells. J Neurophysiol 74:574-81
Tomsig, J L; Suszkiw, J B (1995) Multisite interactions between Pb2+ and protein kinase C and its role in norepinephrine release from bovine adrenal chromaffin cells. J Neurochem 64:2667-73
Sun, L R; Suszkiw, J B (1994) Pb2+ activates potassium currents in bovine adrenal chromaffin cells. Neurosci Lett 182:41-3
Tomsig, J L; Suszkiw, J B (1993) Intracellular mechanism of Pb(2+)-induced norepinephrine release from bovine chromaffin cells. Am J Physiol 265:C1630-6
Shao, Z; Suszkiw, J B (1991) Ca2(+)-surrogate action of Pb2+ on acetylcholine release from rat brain synaptosomes. J Neurochem 56:568-74
Tomsig, J L; Suszkiw, J B (1991) Permeation of Pb2+ through calcium channels: fura-2 measurements of voltage- and dihydropyridine-sensitive Pb2+ entry in isolated bovine chromaffin cells. Biochim Biophys Acta 1069:197-200
Tomsig, J L; Suszkiw, J B (1990) Pb2(+)-induced secretion from bovine chromaffin cells: fura-2 as a probe for Pb2+. Am J Physiol 259:C762-8

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